“…BC contain a valuable source of bioactive compounds especially anthocyanins, proanthocyanidins, phenolic acids, flavonoids, and also vitamin C [ 7 ]. Since ancient times, BC have been generally used in European folk medicines to treat arthritis, rheumatism, and respiratory problems [ 8 ] due to its antioxidant, anti-inflammatory, and antimicrobial activities, as well as its vasomodulatory, antihemostatic, and muscle-relaxing effects, and even some neuroprotective and cancer-preventive activities [ 6 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ]. Chrysanthellum americanum , a genus of yellow flowering plants in the Chrysanthemum family [ 16 , 17 ], grows mainly in the mountainous regions or moderate altitude areas in Africa from Senegal to Nigeria and South America from southern Mexico to northern Brazil [ 18 , 19 ].…”