Phenolic Content, Antioxidant and Antimicrobial Activities of Two Fruit Varieties of Algerian Ficus carica L

Abstract

The present study deals with the evaluation of the in vitro antioxidant and antimicrobial potential of four different extracts of two varieties (Azendjar and Taamriout) of dried figs (Ficus carica L.) by using the 2,2-diphenyl-2-picrylhydrazyl radical and agar diffusion methods and minimum inhibitory concentration (MIC)-determination. Moreover, the extracts were investigated for their polyphenolic, flavonoidal and tannin content by using the Folin-Ciocalteu assay, the aluminium trichloride method and precipitation with casein, respectively. The results showed that the highest antioxidant capacity was exhibited by the methanol extract of Azendjar variety with IC50 of 0.080 mg/mL. All extracts possessed more or less antimicrobial activity against the tested Gram-positive and Gram-negative bacteria. Candida albicans was the most susceptible microorganism to all extracts. Pronounced antimicrobial activity was observed by the methanolic extract of Taamriout variety (MIC values 32-128 mg/mL). Moreover, the results showed that the phenolic compounds and flavonoids were abundant in acetone and aqueous extracts.

Synergetic Hepatoprotective Effect of Phenolic Fractions Obtained from Ficus Carica Dried Fruit and Extra Virgin Olive Oil on CCL4 -Induced Oxidative Stress and Hepatotoxicity in Rats

“…In recent study, the total phenolic content in dried fig fruits was analyzed using an oxidation–reduction colorimetric assay (Folin–Ciocalteu reagent) (Debib et al . ) which showed that dark fig fruits were richer in polyphenols than the green varieties. The flavonoid composition of the peel and pulp of two Italian fresh fig cultivars ( F. carica ) were analyzed by Del Caro and Piga (), using the HPLC–DAD method.…”

In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract

“…9 Due to the presence of phenolic acids such as chlorogenic acid, quercetin-3-0-rutinoside (peels), and psoralen (pulp), Ficus fruits are utilized for the treatment of skin depigmentation. 24 Yang et al 25 reported that the methanolic extract of F. carica fruit showed the IC 50 value of 80.0 μg/mL, whereas the water extract of fruit showed the IC 50 value of 720.0 μg/mL in the DPPH model. Similarly, the water extract of the fruit also showed a moderate superoxide radical scavenging activity with the IC 50 value of 950.0 μg/mL.…”

Volatile profile of Greek dried white figs (Ficus carica L.) and investigation of the role of β‐damascenone in aroma formation in fig liquors

“…These herbals were based on ancient Greek authors, especially Dioscorides ( De Materia Medica , BC 78–77) and Galen, as also on references of Hippocrates ( Corpus Hippocratium: On Ancient Medicine, On Aliment or Nutriment , BC 460–377) appreciating fig as a phytonutrient. Its medicinal benefits include metabolic, cardiovascular, antispasmodic, antiviral, antioxidant, antibacterial and anti‐inflammatory remedies, as also potential anticancer activity …”