Phenolic glycosides from the peels of durian fruits Durio zibethinus L.

Abstract

In the present study, six phenolic glycosides, including one new durianol F (1) and five known compounds, durianol A (2), syringaresinol glucoside (3), 4‐O‐β‐glucopyranosyl sinapic acid methyl ester (4), quercetin‐3‐glucopyranoside (5), and quercetin‐3‐rhamnopyranoside (6) were isolated from a methanol extract of the peels of durian fruits (Durio zibethinus). Their chemical structures were elucidated using the NMR and MS spectroscopic analyses and comparision with the previously reported values. In addition, their cytotoxic effect against three human carcinoma cell lines, including liver (HepG2), breast (MCF7), and lung (SK‐LU‐1) was also evaluated.