“…Accurate and reliable data can be obtained by addressing and improving various avenues in LC-MS based analytical methods such as (i) chromatography, (ii) sample preparation and extraction protocols, and (iii) matrix effects. The last decade has seen many studies on profiling phenolicsparticularly the ones associated with the phenylpropanoid pathway (Meyermans et al, 2000;Chen et al, 2003;Damiani et al, 2005;Lin et al, 2009;Callipo et al, 2010;Frolov et al, 2013;Reuben et al, 2013;Ferreres et al, 2014;Eudes et al, 2015;Šibul et al, 2016). Nevertheless, these analytical methods have scope for improvement in one or more of the following: (i) canvassing a larger range of intermediates, (ii) accounting for signal suppression because of matrix effects, (iii) simplifying cumbersome extraction procedures.…”