Phénolstéroides urinaires

Mf, Jayle; Scholler, R; M, Heron; Metay, S

doi:10.1016/0009-8981(59)90142-1

Cited by 9 publications

(1 citation statement)

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“…None of the patients showed clinical and/or biological evidence of acromegaly; lack of thyroid disturbance was assessed by radio-immunological deter¬ minations of T3 and T4; a normal adrenocortical function was assessed by competi¬ tive-protein-binding assay of plasma corticosteroids and by measurement of 24 h urinary 17-hydroxysteroids and 17-ketosteroids. The urinary 24 h total oestrogens, as assessed by the technique of Jayle (Jayle et al 1959), are indicated for each patient in Table 1: with the exception of 3 cases, all values are below the range (20-40 /ig/day) of values normally encountered in the follicular phase of the ovulatory cycle.…”

Section: Material Patients and Methodsmentioning

confidence: 99%

Hypogonadism, Galactorrhoea and Hyper-Prolactinaemia: Evaluation of Pituitary Gonadotrophins Reserve Before and Under Bromocriptine

M¹,

L’Hermite²,

Hedouin-Quincampoix³

et al. 1977

Acta Endocrinologica

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Twenty patients with hypogonadism (19 women with amenorrhoea and 1 man with impotence and infertility), galactorrhoea and hyper-prolactinaemia (range: 36 to 344 ng/ml) were studied. The radiological study of the sella turcica, including in all cases hypocycloidal tomograms, allowed classification of the patients into 3 groups: group I (n = 4) had a grossly enlarged sella turcica, group II (n = 12) had localized alterations indicating the probable existence of a prolactin-secreting microadenoma ("microdeformation") while group III patients presented no radiological abnormality. Before treatment, all the patients were submitted to a complete evaluation of the function of their anterior pituitary, including the LH and FSH responses to iv administration of Gn-RH. All the group I patients had low basal LH levels and a blunted response to Gn-RH. The basal LH and in response to Gn-RH were normal in most of the group II patients and in all of the group III patients. An exaggerated FSH response to Gn-RH was observed in 6/12 patients with microdeformation (group II) but not in groups I and III patients. A low LH and a blunted 84 (1977) 738-749 Services d'Endocrinologie et de Médecine Generale, (Prof. M. Linquette et P. Fossati),

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Section: Material Patients and Methodsmentioning

confidence: 99%