Phenomena of biocide resistance in microorganisms

Heinzel, M.

doi:10.1016/s0964-8305(98)00028-6

Cited by 61 publications

(37 citation statements)

References 19 publications

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“…This fact makes us consider the reasons of this phenomenon. In accordance with the references (Jatzwauk 1984;Heinzel 1998;Russell et al 1998;McDonnell et al 1999) we can expect the fact, that resistant strains of microbes have in their population a much higher number of cells, that are very sensitive and very resistant to the prejudice of the part of individuals with the average resistance. This phenomenon may be related to the different course of growth curves and the different number of starving cells in inoculum.…”

Section: Resultssupporting

confidence: 86%

Evaluation by Conductance Assay of Shiga Toxin-Producing Escherichia coli (STEC) O157 and O26 and teir Sensitivity to Selected Disinfectants

J¹,

Pokludová²,

Novotná³

et al. 2003

Acta Vet. Brno

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The sensitivity of field isolates of STEC O157, O26 and reference strains from collections to different concentrations of sodium hypochlorite, sodium benzensulfochloramid (chloramine B), glutaraldehyde with glyoxal, peracetic acid and lactic acid was verified. The most effective disinfectant was peracetic acid at the concentration of 0.02%, followed by chloramine B and lactic acid at the concentration of 0.5%. The field isolate of STEC O157 in comparison with the other tested strains of E. coli was more resistant to the activity of peracetic both and lactic acid and to chlorine releasing disinfectants. Its resistance was comparable to that of reference E. coli strain CNCTC 301/60, which is the reference micro-organism for efficacy testing of disinfectants. Statistically significant difference among the individual tested strains was not found. Differences between the tested STEC strains and reference strains in evaluation of growth curves were shown. STEC O157 and O26, more than the other tested strains, showed a higher resistance to acid environment in this characteristic. The reference E. coli strain CNCTC 301/60 and field isolate STEC E. coli O157 were the most resistant of all the tested strains, reference non toxigenic E. coli O157 strain was the most resistant to aldehydes.

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Section: Resultssupporting

confidence: 86%

Evaluation by Conductance Assay of Shiga Toxin-Producing Escherichia coli (STEC) O157 and O26 and teir Sensitivity to Selected Disinfectants

J¹,

Pokludová²,

Novotná³

et al. 2003

Acta Vet. Brno

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“…In particular the absence of MspA might considerably change the interactions of lipids in the outer membrane of M. smegmatis, considering that it is the most abundant protein in M. smegmatis (29). Such an effect might also account for the moderate loss of susceptibility against formaldehyde in porin mutants of Escherichia coli and Serratia marcescens (14).…”

Section: Resultsmentioning

confidence: 99%

Importance of Porins for Biocide Efficacy against Mycobacterium smegmatis

Frenzel

Schmidt

Niederweis

et al. 2011

Appl Environ Microbiol

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“…A number of mechanisms account for the wide range of sensitivity noted for the antibacterial action of antibiotics and biocides (116). Some organisms and genera, by virtue of the absence of critical target sites or an inability of the agents to accumulate at those targets, are intrinsically resistant to particular groups of agents under all growth conditions (110).…”

Section: Factors That Affect Biocide Susceptibilitymentioning

confidence: 99%

Potential Impact of Increased Use of Biocides in Consumer Products on Prevalence of Antibiotic Resistance

2003

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There has recently been much controversy surrounding the increased use of antibacterial substances in a wide range of consumer products and the possibility that, as with antibiotics, indiscriminate use of biocides might contribute to the overall pattern of susceptibility in the general environment and in the clinic. Such speculation, based on the isolation of resistant mutants from in vitro monoculture experiments, is not reflected by an emergence of biocide-resistant strains in vivo. This review provides a broad coverage of the biocide and resistance literature and evaluates the potential risks, perceived from such laboratory monoculture experiments, against evidence gathered over 50 years of field studies. An explanation for the continued effectiveness of broad-spectrum biocidal agents against the decline in efficacy of therapeutic agents is provided based on the fitness costs of resistance and the ubiquity of naturally occurring substances that possess antibacterial effect. While we conclude from this review of the literature that the incorporation of antibacterial agents into a widening sphere of personal products has had little or no impact on the patterns of microbial susceptibility observed in the environment, the associated risks remain finite. The use of such products should therefore be associated with a clear demonstration of added value either to consumer health or to the product life. Hygienic products should therefore be targeted to applications for which the risks have been established

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Phenomena of biocide resistance in microorganisms

Cited by 61 publications

References 19 publications

Evaluation by Conductance Assay of Shiga Toxin-Producing Escherichia coli (STEC) O157 and O26 and teir Sensitivity to Selected Disinfectants

Evaluation by Conductance Assay of Shiga Toxin-Producing Escherichia coli (STEC) O157 and O26 and teir Sensitivity to Selected Disinfectants

Importance of Porins for Biocide Efficacy against Mycobacterium smegmatis

Potential Impact of Increased Use of Biocides in Consumer Products on Prevalence of Antibiotic Resistance

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