Phenotypes of Escherichia coli isolated from urine: Differences between extended-spectrum β-lactamase producers and sensitive strains

Abstract

These findings suggest a potential to detect ESBL strains based on virulence factors and biochemical properties, which could be useful in shaping proper empiric antimicrobial therapy, and for initiating such therapy as soon as possible.

Multidrug resistance dissemination by extended-spectrum β-lactamase-producing Escherichia coli causing community-acquired urinary tract infection in the Central-Western Region, Brazil

“…Extended-spectrum -lactamase (ESBL)-producing UPEC clones are commonly related to MDR extraintestinal pathogens, thus further limiting the treatment options for UTI therapy. These clones are frequently associated with the production of CTX-M enzymes, currently the most widespread ESBLs [2,3]. These strains are resistant to oxyimino-cephalosporins and monobactams and are frequently co-resistant to fluoroquinolones [1].…”

Relationship between Hemolysis and Resistance to Antibiotics among Clinical Isolates of Escherichia Coli from Urine

“…The percentages of isolates with resistance to both levofloxacin ciprofloxacin, cefepime but not to other agents, were significantly higher (P< 0.05) among NHEC isolates than among HEC isolates. Although fluoroquinolone use is now discouraged, this finding may represent a narrow indication for its use in certain clinical scenarios [3][4][5][6].…”