2022
DOI: 10.1080/14740338.2022.2058487
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Phenytoin and damage to the cerebellum – a systematic review of published cases

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Cited by 8 publications
(5 citation statements)
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References 24 publications
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“…The search strategy included the combination of 15 movement disorders (akathisia, athetosis, bruxism, chorea, dyskinesia, dystonia, myoclonus, Parkinson or Parkinson's disease, Parkinsonism, paroxysmal dyskinesias, restless legs syndrome, stereotypy, tic, Tourette, and tremor) and 24 ASDs (brivaracetam, carbamazepine, cenobamate, clonazepam, eslicarbazepine, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, oxcarbazepine, perampanel, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, stiripentol, tiagabine, topiramate, valproate, vigabatrin, and zonisamide); the last date of search was 17 April, 2022. Painful legs and moving toe syndrome and ataxia were not included among the search terms respectively because of the rarity of the disorder and the common presentation of ASD-related toxicity [6], already extensively reviewed in the literature [7] [8]. In addition, cortical myoclonus of epileptic origin was not the focus of our review as it is included among the epileptic syndromes and its treatment has been discussed elsewhere [9].…”
Section: Literature Searchmentioning
confidence: 99%
“…The search strategy included the combination of 15 movement disorders (akathisia, athetosis, bruxism, chorea, dyskinesia, dystonia, myoclonus, Parkinson or Parkinson's disease, Parkinsonism, paroxysmal dyskinesias, restless legs syndrome, stereotypy, tic, Tourette, and tremor) and 24 ASDs (brivaracetam, carbamazepine, cenobamate, clonazepam, eslicarbazepine, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, oxcarbazepine, perampanel, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, stiripentol, tiagabine, topiramate, valproate, vigabatrin, and zonisamide); the last date of search was 17 April, 2022. Painful legs and moving toe syndrome and ataxia were not included among the search terms respectively because of the rarity of the disorder and the common presentation of ASD-related toxicity [6], already extensively reviewed in the literature [7] [8]. In addition, cortical myoclonus of epileptic origin was not the focus of our review as it is included among the epileptic syndromes and its treatment has been discussed elsewhere [9].…”
Section: Literature Searchmentioning
confidence: 99%
“…Um dos sintomas clássicos da atrofia do cerebelo é a ataxia, descrita como uma das principais lesões irreversíveis que afetam a coordenação motora, sendo caracterizada pela realização de movimentos incertos, inseguros e descoordenados, imprecisão em alcançar uma posição da extremidade final e oscilações durante o curso do movimento, afetando diretamente a realização da marcha, (Ferner, 2022;Calsani, 2007;Rissardo & Caprara 2022). Com isto, o quadro motor do paciente se torna debilitado, pois a marcha é um fator essencial para a qualidade de vida dos indivíduos (Guirao-Bringas, & Díaz-Pérez, 2012).…”
Section: Resultsunclassified
“…All participants in our cohort are right-handed ( 31 , 36 ). Exclusion criteria included: (1) Those who had a psychiatric or neurological disorder other than MTLE, (2) Those who had a cerebral or cerebellar lesion other than HS, (3) Those who were below 16 or over 65 years of age, (4) Those who were unable to endure or comprehend the procedure, (5) Those who had poor imaging quality, including excessive head motion or poor task effect, and (6) Those who received phenytoin treatment ( 37 ).…”
Section: Methodsmentioning
confidence: 99%