Pheochromocytoma and paraganglioma—an update on diagnosis, evaluation, and management

Jain, Amrish; Baracco, Rossana; Kapur, Gaurav

doi:10.1007/s00467-018-4181-2

Cited by 100 publications

(103 citation statements)

References 63 publications

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“…The gold standard treatment is surgical resection of the tumor, with very strict preoperative preparation to control blood pressure using adrenergic blockade [ 8 ], laparoscopy should be preferred to open abdomen unless the tumor size exceeds 8 cm, uncertain diagnosis or a contraindication to laparoscopy as well as the surgeon expertise and the lateral or anterior trans peritoneal approach is ideally considered unless the patient has a history of previous abdominal surgery or a bilateral adrenalectomy then the posterior approach is required so no position changing will be needed [ 7 ]…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of a 09 cm pheochromocytoma mistaken to be an intramesenteric pancreatic tumor: Case report complying with the scare guidelines

Zahrarahou

Miry

Mirali

et al. 2021

International Journal of Surgery Case Reports

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Highlights Pheochromocytoma’s case reports keep showing its diversity in clinical presentation, diagnosis methods treatment and follow up challenges. The diagnosis is basically simple by biomarkers testing, an imaging and challenging when biologically the tumor is silent. Functional imaging should be used to locate the tumor or its metastasis. Preoperative measures should be taken so no major preoperative complications and the main treatment is the tumor complete resection. The malignancy of the pheochromocytoma is not easy to be identified which imposes a lifetime follow up of these patients as metastasis were described even after 40 years after diagnosis.

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Section: Discussionmentioning

confidence: 99%

Diagnosis of a 09 cm pheochromocytoma mistaken to be an intramesenteric pancreatic tumor: Case report complying with the scare guidelines

Zahrarahou

Miry

Mirali

et al. 2021

International Journal of Surgery Case Reports

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“…We initiated antihypertensive therapy with phenoxybenzamine as α blockade along with subsequent expansion of the therapy with a β-blocker. 3,4 Treatment was initiated after meta-iodobenzylguanidine scintigraphy to avoid interference causing false-negative results. 5 Pathologic examination of the removed tumor confirmed pheochromocytoma.…”

Section: Discussionmentioning

confidence: 99%

Arterial Hypertension in a 10-Year-Old Girl

Meeser

Beck

Dübbers

et al. 2021

American Journal of Kidney Diseases

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“…The classic symptoms of catecholamine excess include headaches, diaphoresis and palpitations, which may be episodic in nature. This triad of the disease is present in about 54% of patients (3). The most common symptom in children, present in 60-90% of cases, is sustained hypertension (2).…”

Section: Introductionmentioning

confidence: 99%

Catecholamine-induced Myocarditis in a Child with Pheochromocytoma

Ucakturk¹,

Mengen²,

Azak³

et al. 2020

Jcrpe

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Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors. The clinical presentation of pediatric PPGLs is highly variable. In cases with pheochromocytoma (PCC), excess catecholamine may stimulate myocytes and cause structural changes, leading to life-threatening complications ranging from stress cardiomyopathy (CM) to dilated CM. Herein, we report the case of catecholamineinduced myocarditis in a child with asymptomatic PCC. A 12-year-and-2-month-old male patient with a known diagnosis of type-1 neurofibromatosis was brought to the emergency department due to palpitations and vomiting. On physical examination, arterial blood pressure was 113/81 mmHg, pulse was 125/min, and body temperature was 36.5 °C. Laboratory tests showed a leucocyte count of 12.8x10 3 µL/L and a serum C-reactive protein level of 1.1 mg/dL (Normal range: 0-0.5). Thyroid function tests were normal, while cardiac enzymes were elevated. Electrocardiogram revealed no pathological findings other than sinus tachycardia. The patient was diagnosed with and treated for myocarditis as echocardiography revealed a left ventricular ejection fraction of 48%. Viral and bacterial agents that may cause myocarditis were excluded via serological tests and blood cultures. Blood pressure, normal at the time of admission, was elevated (140/90 mmHg) on the 5 th day of hospitalization. Magnetic resonance imaging revealed a 41x46x45 mm solid adrenal mass. The diagnosis of PCC was confirmed by elevated urinary and plasma metanephrines. The patient underwent surgery. Histopathology of the excised mass was compatible with PCC. It should be kept in mind that, even if there are no signs and symptoms of catecholamine elevation, CM may be the first sign of PCC.

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Pheochromocytoma and paraganglioma—an update on diagnosis, evaluation, and management

Cited by 100 publications

References 63 publications

Diagnosis of a 09 cm pheochromocytoma mistaken to be an intramesenteric pancreatic tumor: Case report complying with the scare guidelines

Diagnosis of a 09 cm pheochromocytoma mistaken to be an intramesenteric pancreatic tumor: Case report complying with the scare guidelines

Arterial Hypertension in a 10-Year-Old Girl

Catecholamine-induced Myocarditis in a Child with Pheochromocytoma

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Pheochromocytoma and paraganglioma—an update on diagnosis, evaluation, and management

Cited by 100 publications

References 63 publications

Diagnosis of a 09 cm pheochromocytoma mistaken to be an intramesenteric pancreatic tumor: Case report complying with the scare guidelines

Diagnosis of a 09 cm pheochromocytoma mistaken to be an intramesenteric pancreatic tumor: Case report complying with the scare guidelines

Arterial Hypertension in a 10-Year-Old Girl

Catecholamine-induced Myocarditis in a Child with Pheochromocytoma

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Diagnosis of a 09 cm pheochromocytoma mistaken to be an intramesenteric pancreatic tumor: Case report complying with the scare guidelines

Diagnosis of a 09 cm pheochromocytoma mistaken to be an intramesenteric pancreatic tumor: Case report complying with the scare guidelines