Philodendron scandens Koch et Sello subsp. oxycardium (Schott) Bunting, a New Source of Allergenic Alkyl Resorcinols.

Reffstrup, Torsten; Hammershøy, Ole; Pm, Boll; Schmidt, H. E.

doi:10.3891/acta.chem.scand.36b-0291

Cited by 30 publications

(18 citation statements)

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“…Leaves and stems of Philodendron scadens subsp. oxycardium contain the anacardic acid derivative 42 (0.016% of FM) and the AR 29 (0.005% from FM), which is the major allergen compound and a weapon defense of the plant [48]. The AR 29 has various origins and can also be isolated from liverwort Omphalantus filiformis [49] (mainly in the cuticle) and leaves of Stylogyne turbacensis [50].…”

Section: Natural Sourcesmentioning

confidence: 99%

Omega-3 polyunsaturated lipophenols, how and why?

et al. 2016

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Polyphenols and n-3 polyunsaturated fatty acids (PUFAs) are two classes of natural compounds, which have been highlighted in epidemiological studies for their health benefits. The biological activities of those two families of metabolites on oxidation, inflammation, cancer, cardiovascular and degenerative diseases have been reported in vitro and in vivo. On the other hand, chemical bonding between the two structures leading to n-3 lipophenol derivatives (or phenolipids) has been studied in numerous works over the last decade, and some examples could also be found from natural sources. Interest in lipophilization of phenolic structures is various and depends on the domain of interest: in food industry, the development of lipidic antioxidants could be performed to protect lipidic food matrix from oxidation. Whereas, on pharmaceutical purpose, increasing the lipophilicity of polar phenolic drugs could be performed to improve their pharmacological profile. Moreover, combining both therapeutic aspects of n-3 PUFAs and of polyphenols in a single lipophenolic molecule could also be envisaged. An overview of the synthesis and of the natural sources of n-3 lipophenols is presented here, in addition to their biological activities which point out in several cases the benefit of the conjugated derivatives.

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Section: Natural Sourcesmentioning

confidence: 99%

Omega-3 polyunsaturated lipophenols, how and why?

et al. 2016

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“…Alkylresorcinols (AR) are amphiphilic phenolic lipids found in plants from a number of different families notably the Anacardiaceae (such as poison ivy, cashew nut shell, poison oak), Proteaceae (such as Grevilla pyramidalis), Gramineae (such as cereal grains), Araceae (such as Philodendron scandens), and certain bacterial and algae sources (Madrigal et al 1977, Tyman 1979, Reffstrup et al 1982, Reffstrup and Boll 1985, Bandyopadhyay et al 1985.…”

mentioning

confidence: 99%

Effects of Fermentation and Baking of Whole Wheat and Whole Rye Sourdough Breads on Cereal Alkylresorcinols

Winata

Lorenz

1997

Cereal Chem

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Cereal Chem. 74(3):284-287Alkylresorcinol (AR) content was determined in multiple-stage whole wheat and whole rye flour sours, as well as in whole wheat and whole rye flour doughs and breads. AR content decreased considerably during fermentation and baking. AR content was reduced by 20 and 46%, respectively, at the end of sourdough starter fermentation of whole wheat and whole rye flour sours. AR content, which was 512 and 210 µg/g in whole rye and whole wheat flour doughs, respectively, was 30 and 0 µg/g, respectively, after baking of breads. Synthetic AR added at different levels to doughs was also greatly reduced during fermentation and baking. 2 Corresponding author. Fax: 970/491-7252.

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“…Kozubek, 1987;Bitkov et al, 1990). In Philodendron their presence is associated with allergenic effects (Reffstrup et al, 1982;Reffstrup & Boll, 1985) and their location in the cuticle is said to be defensive. In this respect they resemble the urushiols of the Anacardiaceae which are derivatives of catechol rather than resorcinol (Gross, Baer & Fales, 1975).…”

Section: Nitrogenous Sugar Analogues @O%hydroay Alkaloids)mentioning

confidence: 99%

“…A proteolytic enzyme, 'dumbcain', has been described in much earlier work and suggested as the active agent (Walter & Khanna, 1972). In searching for alternative chemical possibilities attention is drawn to allergenic long chain alkylresorcinols identified in Philodendron (Reffstrup et al, 1982;Reffstrup & Boll, 1985). In addition, a proteolytic enzyme was described in Dieflmbachia which may be responsible for some of the symptoms, although other potentially active substances, such as histamine and cyanogenic glycosides, were also noted (reviewed Arditti & Rodriguez, 1982).…”

Section: Introductionmentioning

confidence: 99%