Phosphorylated guanosine derivatives of eukaryotes: Regulation of DNA-dependent RNA polymerases I, II, and III in fungal development

McNaughton, David R.; Klassen, Glen R.; LéJohn, Herb B.

doi:10.1016/0006-291x(75)90534-3

Cited by 20 publications

(4 citation statements)

References 11 publications

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“…Apart from polypeptide factors that interact with RNA polymerases and regulate their transcriptive specificity, several other naturally occurring substances of low molecular weight have been shown to regulate the activities of various RNA polymerases in plants and fungi (Arens & Stout, 1974;LeJohn, Cameron, McNaughton & Classen, 1975 ;McNaughton et al 1975). Nucleoside polyphosphates, with inhibitory or stimulatory effects on RNA polymerases have been found to occur in a number of fungi including Achlya sp., Blastocladiella emersonii, Aspergillus niger, and Rhixopus stolonifer.…”

Section: ( 2 ) Role Of Inducer Moleculesmentioning

confidence: 99%

A Possible Molecular Basis for Obligate Host‐pathogen Interactions

Chakravorty

Shaw

1977

Biological Reviews

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Section: ( 2 ) Role Of Inducer Moleculesmentioning

confidence: 99%

A Possible Molecular Basis for Obligate Host‐pathogen Interactions

Chakravorty

Shaw

1977

Biological Reviews

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“…Diadenosine and diguanosine tetraphosphates are molecules of potential interest in metabolic regulation (Lobatón et al, 1975). Besides the effect here described for Gp4G, this nucleotide seems to also have a regulatory role on the RNA polymerases from several fungi (McNaughton et al, 1975).…”

Section: Discussionmentioning

confidence: 57%

Guanosine monophosphate reductase from Artemia salina: inhibition by xanthosine monophosphate and activation by diguanosine tetraphosphate

Renart¹,

Renart²,

Sillero³

et al. 1976

Biochemistry

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In the course of studies on the metabolic role of diguanosine tetraphosphate during development of Artemia salina, a guanosine monophosphate (GMP) reductase has been found and partially purified from the 150 OOOg Artemia cysts supernatant. From Lineweaver-Burk plots, two apparent Km values of 5 and 50 µ were obtained for GMP. Xanthosine monophosphate (XMP) is a very strong inhibitor of the reaction. In the presence of 1.5 µ XMP hyperbolic kinetics are found. Diguanosine tetraphosphate counteracts .very effectively

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“…The presence of diguanosine nucleotides, which were presumed to control transcription (58), was reported in fungi (47), but Goh and LeJohn have since retracted their original characterization of these compounds, which they refer to as HS-1, -2, and -3 (28). The absence of .…”

Section: Unclassified Structuresmentioning

confidence: 99%