Photo Allergic Contact Dermatitis: The 15-Year Experience of a Tertiary Reference Center in a Sunny Mediterranean City

Κατσαρού, Αλεξάνδρα; Makris, Michaël; Zarafonitis, G; Lagogianni, Eirini; Gregoriou, Stamatis; Kalogeromitros, D.

doi:10.1177/039463200802100327

Cited by 26 publications

(10 citation statements)

References 10 publications

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“…Our reactions occurred with the low concentration (0.1% pet.) and were relevant, as in a recent study from Greece (8). Because of its high phototoxic and photosensitizing potential, this drug should be removed from the market, as has already happened in France with its analogue chlorproethazine contained in Neuriplege™ cream (Genevrier, Antibes, France) that was shown to be phototoxic and photoallergic (7, 9, 10).…”

Section: Discussionmentioning

confidence: 98%

Photopatch testing with an extended series of photoallergens: a 5‐year study

et al. 2009

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Objective: We conducted a retrospective study evaluating the results of photopatch tests (PPTs) performed with an extended series with the objective of determining the main photoallergens in our region and whether they would be detected by a recently recommended baseline PPT series.Materials and methods: 83 patients (58 females/25 males, mean age 54.8 years) were tested with a photoallergen series, and among these, 30 were also tested with a non-steroidal anti-inflammatory drug (NSAID) series, irradiated at D2 with 5 J/cm 2 ultraviolet A (UVA).Results: Thirty-six of 83 patients (43.3%) had at least one positive reaction, with 21 (25.3%) reacting in the photoallergen series. The main relevant reactions were as follows: 10 to ultraviolet filters (benzophenone-3 and benzophenone-4, 3 patients each), 7 to promethazine, and 2 to chlorpromazine. Twenty of 30 patients tested (70%) had a relevant positive PPT to an NSAID, 9 to piroxicam because of systemic photosensitivity, 8 to benzydamine from a topical gel or oral solution, and 2 to ketoprofen. Conclusions:Our results are discordant with most recently published studies because of the particularities of the population studied and to regional prescribing habits. Therefore, apart from the recommended baseline series of photoallergens, other substances must be tested according to regional peculiarities.

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Section: Discussionmentioning

confidence: 98%

Photopatch testing with an extended series of photoallergens: a 5‐year study

et al. 2009

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“…Living in a tropical area does not seem to predispose individuals to developing a photoallergic reaction. The prevalences of the positive photoallergic reactions and common photoallergens found in various countries are summarised in Figure 1 1,2,5,7‐21 …”

Section: Discussionmentioning

confidence: 99%

Photopatch testing in a tropical country, Thailand: 20 years' experience

Chaiyabutr

Sukakul

Limphoka

et al. 2020

Photoderm Photoimm Photomed

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Background: Photoallergic contact dermatitis is one of the important parts of photodermatoses. The investigation of choice is photopatch testing. However, reports with photopatch test results from Asian countries are scarce. The objective of this study was to determine the prevalence of positive photopatch test reactions and to ascertain the common photoallergens among Thai patients during 1998-2018. Methods: We retrospectively reviewed the records of 339 patients who were clinically suspected of having photoallergic contact dermatitis and had undergone photopatch testing. Results: A total of 44 photoallergic contact reactions in 38 patients (11.2%) were found. The positive photoallergic reactions were mainly found with organic ultraviolet filters and fragrances. Conclusions: Organic ultraviolet filter chemicals especially benzophenone-3 and fragrances were found to have a high prevalence of photoallergic contact reactions. Monitoring of the photoallergens employed in photopatch tests should be conducted periodically to provide the best patient care.

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“…Chlorpromazine is a classic antipsychotic drug belonging to the aliphatic phenothiazine group that is known to produce both systemic phototoxic and photoallergic reactions . This drug may also cause photoallergic contact dermatitis and, albeit exceptionally, allergic contact dermatitis (ACD) . Photoallergic contact dermatitis to chlorpromazine typically develops in professional health workers or nonprofessional caregivers .…”

Section: Introductionmentioning

confidence: 99%