Photoacoustic Tomography Imaging: An Emerging Detection Way

Imaging of Gastrointestinal Tract Ailments

“…PAT uses laser pulses to create photoacoustic waves that are generated when absorbed light is converted into heat, leading to localized thermoelastic expansion and subsequent ultrasound waves, then detected by ultrasonic sensors, which are then analyzed to produce images. PAT is essentially optical imaging, good acoustic spatial resolution can be achieved even at imaging depths of 5–6 cm, making it suitable for imaging deeper structures in the GI tract [ 11 , 33 ]. PAT has high sensitivity and can detect molecular-level changes in tissues, making it a promising tool for clinical images, such as tumor diagnosis imaging [ 34 , 35 ], whole-body imaging of small animals [ 36 ], and various other medical applications [ 37 ].…”

Folic acid modified Pluronic F127 coating Ag2S quantum dot for photoacoustic imaging of tumor cell-targeting

“…After laser pulse energy is absorbed by biological tissue, the instantaneous rise of temperature leads to the expansion of transient thermoelastic stress, which propagates to the outside of the tissue in the form of a pressure wave to cause an ultrasonic wave (PA signal). As a new imaging method, PAI combines the advantages of optical imaging and ultrasound imaging, with high safety levels, high resolution and a deep depth of imaging [5]. Not only can it be used for tissue structure imaging, but it also can be applied to biological function imaging [6].…”