Photocatalytic decomposition of A549-lung cancer cancer cells by TiO2 nanoparticles

Balachandran, K.; Mageswari, S.; Preethi, A.

doi:10.1016/j.matpr.2020.06.297

Cited by 6 publications

(9 citation statements)

References 25 publications

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“…The particle size distribution (PSD) is shown in Figure 6 f and indicates that the average particle size (PS) of the as-prepared TiO 2 nanoparticles was 34.89 ± 3.37 nm. The obtained data further confirm the findings of BET, SEM, and EDS analyses [ 53 , 54 ].…”

Section: Resultssupporting

confidence: 89%

Biochar of Spent Coffee Grounds as Per Se and Impregnated with TiO2: Promising Waste-Derived Adsorbents for Balofloxacin

2021

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Biochars (BC) of spent coffee grounds, both pristine (SCBC) and impregnated with titanium oxide (TiO2@SCBC) were exploited as environmentally friendly and economical sorbents for the fluroquinolone antibiotic balofloxacin (BALX). Surface morphology, functional moieties, and thermal stabilities of both adsorbents were scrutinized using SEM, EDS, TEM, BET, FTIR, Raman, and TG/dT analyses. BET analysis indicated that the impregnation with TiO2 has increased the surface area (50.54 m2/g) and decreased the pore size and volume. Batch adsorption experiments were completed in lights of the experimental set-up of Plackett–Burman design (PBD). Two responses were maximized; the % removal (%R) and the adsorption capacity (qe, mg/g) as a function of four variables: pH, adsorbent dosage (AD), BALX concentration ([BALX]), and contact time (CT). %R of 68.34% and 91.78% were accomplished using the pristine and TiO2@SCBC, respectively. Equilibrium isotherms indicated that Freundlich model was of a perfect fit for adsorption of BALX onto both adsorbents. Maximum adsorption capacity (qmax) of 142.55 mg/g for SCBC and 196.73 mg/g for the TiO2@SCBC. Kinetics of the adsorption process were best demonstrated using the pseudo-second order (PSO) model. The adsorption-desorption studies showed that both adsorbents could be restored with the adsorption efficiency being conserved up to 66.32% after the fifth cycles.

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Section: Resultssupporting

confidence: 89%

Biochar of Spent Coffee Grounds as Per Se and Impregnated with TiO2: Promising Waste-Derived Adsorbents for Balofloxacin

2021

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“…Compared to microparticles, titanium dioxide nanoparticles display enhanced catalytic activity [3,5]. This is because a decrease in size leads to an increased surface area available for catalysis [5,10,12,20,21]. Recent breakthroughs have been achieved in medicinal applications of photocatalysis, by testing nano-titania as an anticancer agent [14,20,21].…”

Section: Nanoarchitecture Achievementsmentioning

confidence: 99%

“…This is because a decrease in size leads to an increased surface area available for catalysis [5,10,12,20,21]. Recent breakthroughs have been achieved in medicinal applications of photocatalysis, by testing nano-titania as an anticancer agent [14,20,21]. Balachandran et al reported that irradiated TiO 2 particles below 20 nm are an efficient "photo-killer" of pulmonary cancer cells [20].…”

Section: Nanoarchitecture Achievementsmentioning

confidence: 99%

“…Recent breakthroughs have been achieved in medicinal applications of photocatalysis, by testing nano-titania as an anticancer agent [14,20,21]. Balachandran et al reported that irradiated TiO 2 particles below 20 nm are an efficient "photo-killer" of pulmonary cancer cells [20]. Valence band holes, with their strong oxidant character, lead to the formation of reactive oxygen species; these will interact with defective cells, causing significant intracellular damage, to finally induce their necrosis [20,21].…”

Section: Nanoarchitecture Achievementsmentioning

confidence: 99%

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Titanium Dioxide: Structure, Impact, and Toxicity

Racovita

2022

IJERPH

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Titanium dioxide, first manufactured a century ago, is significant in industry due to its chemical inertness, low cost, and availability. The white mineral has a wide range of applications in photocatalysis, in the pharmaceutical industry, and in food processing sectors. Its practical uses stem from its dual feature to act as both a semiconductor and light scatterer. Optical performance is therefore of relevance in understanding how titanium dioxide impacts these industries. Recent breakthroughs are summarised herein, focusing on whether restructuring the surface properties of titanium dioxide either enhances or inhibits its reactivity, depending on the required application. Its recent exposure as a potential carcinogen to humans has been linked to controversies around titanium dioxide’s toxicity; this is discussed by illustrating discrepancies between experimental protocols of toxicity assays and their results. In all, it is important to review the latest achievements in fast-growing industries where titanium dioxide prevails, while keeping in mind insights into its disputed toxicity.

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“…In addition, TiO 2 NPs show increased catalytic activity as compared to other NPs [ 124 , 126 ]. The reason it became possible was because the smaller size of TiO 2 NPs provides a large surface area for the catalysis to take place [ 126 , 139 , 140 , 141 , 142 ]. If the TiO 2 NPs get very much smaller, then they exhibit a much greater surface area and number of particles per unit mass, which leads to much greater chemical reactivity than is even required [ 143 ].…”

Section: The Titanium Oxide Npsmentioning

confidence: 99%

Medical and Dental Applications of Titania Nanoparticles: An Overview

Mansoor

Khurshid

Khan³

et al. 2022

Nanomaterials

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Currently, titanium oxide (TiO2) nanoparticles are successfully employed in human food, drugs, cosmetics, advanced medicine, and dentistry because of their non-cytotoxic, non-allergic, and bio-compatible nature when used in direct close contact with the human body. These NPs are the most versatile oxides as a result of their acceptable chemical stability, lower cost, strong oxidation properties, high refractive index, and enhanced aesthetics. These NPs are fabricated by conventional (physical and chemical) methods and the latest biological methods (biological, green, and biological derivatives), with their advantages and disadvantages in this epoch. The significance of TiO2 NPs as a medical material includes drug delivery release, cancer therapy, orthopedic implants, biosensors, instruments, and devices, whereas their significance as a dental biomaterial involves dentifrices, oral antibacterial disinfectants, whitening agents, and adhesives. In addition, TiO2 NPs play an important role in orthodontics (wires and brackets), endodontics (sealers and obturating materials), maxillofacial surgeries (implants and bone plates), prosthodontics (veneers, crowns, bridges, and acrylic resin dentures), and restorative dentistry (GIC and composites).

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Photocatalytic decomposition of A549-lung cancer cancer cells by TiO2 nanoparticles

Cited by 6 publications

References 25 publications

Biochar of Spent Coffee Grounds as Per Se and Impregnated with TiO2: Promising Waste-Derived Adsorbents for Balofloxacin

Biochar of Spent Coffee Grounds as Per Se and Impregnated with TiO2: Promising Waste-Derived Adsorbents for Balofloxacin

Titanium Dioxide: Structure, Impact, and Toxicity

Medical and Dental Applications of Titania Nanoparticles: An Overview

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