Photodynamic activity of platinum(IV) chloride surface-modified TiO2 irradiated with visible light

Jańczyk, Agnieszka; Wolnicka-Głubisz, Agnieszka; Urbańska, Krystyna; Kisch, Horst; Stochel, Grażyna; Macyk, Wojciech

doi:10.1016/j.freeradbiomed.2007.12.019

Cited by 50 publications

(30 citation statements)

References 55 publications

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“…However, TiO 2 can be activated by UV light only, which hinders its applications. Improvement of the optical absorption of TiO 2 in the visible region by dye-adsorbed [11,12] or doping [13,14] methods will facilitate the practical application of TiO 2 as a photosensitizer for PDT. When using dye-adsorbed method, the dyes such as hypocrellin B [11] and chlorine e6 [12] themselves are well-known PDT sensitizers and will have influence on the PDT efficiency of TiO 2 .…”

Section: Introductionmentioning

confidence: 99%

“…When using dye-adsorbed method, the dyes such as hypocrellin B [11] and chlorine e6 [12] themselves are well-known PDT sensitizers and will have influence on the PDT efficiency of TiO 2 . For doping method, anionic species are preferred for the doping rather than cationic metals which have a thermal instability and an increase of the recombination centers of carriers [14]. In addition, cationic metals themselves always present cytotoxicity.…”

Section: Introductionmentioning

confidence: 99%

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Study on the visible-light-induced photokilling effect of nitrogen-doped TiO2 nanoparticles on cancer cells

Wang

et al. 2011

Nanoscale Res Lett

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Nitrogen-doped TiO2 (N-TiO2) nanoparticles were prepared by calcining the anatase TiO2 nanoparticles under ammonia atmosphere. The N-TiO2 showed higher absorbance in the visible region than the pure TiO2. The cytotoxicity and visible-light-induced phototoxicity of the pure- and N-TiO2 were examined for three types of cancer cell lines. No significant cytotoxicity was detected. However, the visible-light-induced photokilling effects on cells were observed. The survival fraction of the cells decreased with the increased incubation concentration of the nanoparticles. The cancer cells incubated with N-TiO2 were killed more effectively than that with the pure TiO2. The reactive oxygen species was found to play an important role on the photokilling effect for cells. Furthermore, the intracellular distributions of N-TiO2 nanoparticles were examined by laser scanning confocal microscopy. The co-localization of N-TiO2 nanoparticles with nuclei or Golgi complexes was observed. The aberrant nuclear morphologies such as micronuclei were detected after the N-TiO2-treated cells were irradiated by the visible light.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Study on the visible-light-induced photokilling effect of nitrogen-doped TiO2 nanoparticles on cancer cells

Wang

et al. 2011

Nanoscale Res Lett

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“…The results were observed for the viable and culturable number of bacteria by SPC method, with triplicate experiments giving fairly good reproducibility for which the samples were serially diluted and 1 mL of 10 −4 dilution was plated on bacto nutrient agar and incubated at 37°C for 24 h. For dye exclusion (24,25), one part of 0.4% trypan blue and 0.1 mL of cell suspension was mixed and incubated at room temperature for 3 min. A drop of the mixture was applied to a haemocytometer and the number of viable and dead cells were counted using Olympus binocular microscope.…”

mentioning

confidence: 99%

Elucidation of Cell Killing Mechanism by Comparative Analysis of Photoreactions on Different Types of Bacteria

Swetha

Singh

Minchitha

et al. 2012

Photochem & Photobiology

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The mechanism of biocidal action of nano titania on Escherichia coli and Staphylococcus aureus has been evaluated by various biochemical techniques like lipid peroxidation, hydrolysis of orthonitrophenol β-D-galactopyranoside, estimation of protein-amino acid and bacterial nucleic acids leakage into solution, in addition to morphology studies by electron microscopy (TEM and SEM) and K(+) ion leakage by inductively coupled plasma optical emission spectrometry. The active anatase phase of nano titania has been synthesized by sol-gel and pulverization techniques to obtain particle sizes averaging around 11 nm. The nano semiconductor with a bandgap of 3.2 eV responds well to the UV source to liberate reactive oxygen species (ROS). Gram negative bacteria easily succumb to the ROS at a faster rate than gram-positive bacteria with an observable difference in the mode of attack. The use of analytical techniques revealed the release of peroxidized lipid (26 nmol mL(-1) ) and protein content (370 μg mL(-1)) with a K(+) ion concentration of 22 000 ppb on complete destruction of E. coli.

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“…Nanocomposites composed of TiO 2 and reduced GR, CdS, or PtCl 4 are excellent PDT visible‐light PSs and have demonstrated a relatively high antiproliferative efficiency in HepG2, leukemia HL60, or mouse melanoma cells (S‐91), respectively.…”

Section: Photocatalytic Use Of Tio2 Nanomaterials In Aqueous and Biolmentioning

confidence: 99%

TiO₂‐Based Photocatalysis at the Interface with Biology and Biomedicine

Tomás‐Gamasa

Mascareñas

2019

ChemBioChem

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The conversion of sunlight into chemical energy by using photosynthetic machinery is at the heart of nature and life. Scientists have also learned to use light energy to promote a great variety of chemical reactions, most of which are based on redox processes involving electron‐transfer steps. Indeed, the area of photoredox catalysis has recently emerged as one of the hottest fields in synthetic chemistry. Many of the photoredox reactions discovered so far take place in homogeneous phases, and rely on the use of soluble photoresponsive catalysts. However, in recent years, there have been many advances in the area of heterogeneous photocatalysis, most of which are based on the use of semiconductor materials, such as TiO2, as a key photocatalytic system. These technologies have found different applications, especially in the field of sustainable chemistry and therapy. Herein, some of these applications, and the potential of TiO2‐based photocatalysts in biology and biomedicine, are reviewed.

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Photodynamic activity of platinum(IV) chloride surface-modified TiO2 irradiated with visible light

Cited by 50 publications

References 55 publications

Study on the visible-light-induced photokilling effect of nitrogen-doped TiO2 nanoparticles on cancer cells

Study on the visible-light-induced photokilling effect of nitrogen-doped TiO2 nanoparticles on cancer cells

Elucidation of Cell Killing Mechanism by Comparative Analysis of Photoreactions on Different Types of Bacteria

TiO₂‐Based Photocatalysis at the Interface with Biology and Biomedicine

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Photodynamic activity of platinum(IV) chloride surface-modified TiO2 irradiated with visible light

Cited by 50 publications

References 55 publications

Study on the visible-light-induced photokilling effect of nitrogen-doped TiO2 nanoparticles on cancer cells

Study on the visible-light-induced photokilling effect of nitrogen-doped TiO2 nanoparticles on cancer cells

Elucidation of Cell Killing Mechanism by Comparative Analysis of Photoreactions on Different Types of Bacteria

TiO2‐Based Photocatalysis at the Interface with Biology and Biomedicine

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Product

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TiO₂‐Based Photocatalysis at the Interface with Biology and Biomedicine