Photodynamic diagnostics and therapy of premalignant lesions and cancer: a three-year clinical experience

Sieroń, Aleksander; Adamek, Mariusz; Biniszkiewicz, Tomasz; Cebula, Wojciech; Cieślar, Grzegorz; Kawczyk‐Krupka, Aleksandra; Niepsuj, G; Szygula, Michał; Wojciechowski, Boguslaw; Zieleznik, Witold

doi:10.1117/12.446513

Cited by 3 publications

(6 citation statements)

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“…[3,38] The process of oxygen supply, intensified by ELF-MF, is also amplified by faster neoangiogenesis and changes in rheological features of blood. There is evidence in the world literature [8,13,28] showing changes in plasma stickiness, shape of erythrocytes, a change in ionic permeability, and the reactance of their cellular membranes.…”

Section: Influence Of Mf On Primary Healing Of Wounds In Rats 179mentioning

confidence: 96%

“…The next step in the increase of collagen synthesis is the higher activity of proline 4-hydroxylase, under the influence of an iron ion, which determines the activity of its prosthetic group. [6,12,18,28] The collagen also plays a very important role as a structural element of blood vessels growing to the wound. The increased synthesis of collagen leads to their quicker maturation and increased oxygen supply to healing tissue as well.…”

Section: Influence Of Mf On Primary Healing Of Wounds In Rats 179mentioning

confidence: 99%

“…These fields are characterized by frequencies to 100 Hz, field strength 1-20 mT, and electric field intensity from 150 to 500 V/m. [10,11,28] The following biophysical and biological effects are bases for the use of magnetic fields in the treatment of chronic wounds: [28,29,37] 1. Usage of fields of therapeutic parameters exerts antiphlogistic, antiseptic, and analgesic activities, which have positive influences on wound healing and the patient's frame of mind.…”

Section: Introductionmentioning

confidence: 99%

“…[7,34] It intensifies tissue respiration processes, utilization of oxygen, promotes vasodilatation, angiogenesis, and in consequence, tissue regeneration. [13,21,28] We assumed that low frequency pulsed magnetic field might stimulate the healing process by influencing local homeostatic mechanisms. We observed effects of ELF-MF activities on primary wound healing by picturing the scar in the electron microscope and by measuring the quantity of tissue hydroxyproline.…”

Section: Introductionmentioning

confidence: 99%

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The Influence of Magnetic Fields on the Primary Healing of Incisional Wounds in Rats

Glinka¹,

Sieroń

Birkner³

et al. 2002

Electromagnetic Biology and Medicine

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Our studies were conducted to examine the influence of extremely low frequency magnetic fields (ELF-MF) on skin wound healing in male adults rats. We used 40 Hz and 10 mT sinusoidal fields. We evaluated the rate of wound healing by determining the tissue hydroxyproline concentration and scar imaging in electron microscope. The systemic body response to ELF-MF was detected by analysis of blood morphological and biochemical parameters, such as: RBC, WBC, hemoglobin, hematocrit, reticulocytes, electrolytes, urea, and total protein concentration. ELF-MF induced the increase of hydroxyproline level in scar tissue and intensified the maternity of collagen seen in the electron microscope. The increase of reticulocyte number in blood confirmed that the healing process in experimental animals was supported by the activation of the oxygen supply and utilization processes, as a result of erythropoietic intensification, without simultaneously upsetting cellular energetic processes. We did not obtain changes in biochemical parameters in blood, such as: electrolytes, urea, and total protein concentration, so we concluded that ELF-MF evoked no negative systemic response.

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Section: Influence Of Mf On Primary Healing Of Wounds In Rats 179mentioning

confidence: 96%

Section: Influence Of Mf On Primary Healing Of Wounds In Rats 179mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Influence of Magnetic Fields on the Primary Healing of Incisional Wounds in Rats

Glinka¹,

Sieroń

Birkner³

et al. 2002

Electromagnetic Biology and Medicine

View full text Add to dashboard Cite

show abstract

“…In this method, the fluorescence of endogenous fluorophores and exogenous photosensitizers is induced by monochromatic light and then analyzed digitally with the use of special equipment. 22 Porphyrin-enriched tumor tissue irradiation with a fluorescence excitation system leads to the emission of pink-red fluorescence. This principle is used as a diagnostic procedure and is called photodynamic diagnosis (PDD), also known as fluorescence diagnosis, which is a more precise denomination.…”

Section: Fluorescence Spectroscopymentioning

confidence: 99%

An Insight into the Recent Innovations in Early Detection of Oral Cancer

Arora¹,

Yadav²,

Sharma³

et al. 2016

IJOCRWEB

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Early diagnosis of oral squamous cell carcinoma (OSCC) and potentially malignant lesions and conditions is an attractive strategy to decrease patient morbidity and mortality, and thus scientists engage to find efficient diagnosis and preclinical screening approaches. The screening of patients for potentially malignant and malignant lesions by traditional methods is a historic concept. Appreciation of subtle surface changes of clinically abnormal mucosal lesions using conventional methods in conjunction with new evolving diagnostic tools has gained a lot of enthusiasm in the recent past. Various search engines for the preparation of this manuscript included PubMed, PubMed central, Science Direct, Springerlink, and google.com. This paper highlights the importance of recent adjunctive techniques used in the field of oncology for early diagnosis of oral mucosal lesions.

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Cone Beam Computed Tomography in the Assessment of the Effectiveness of Physical Therapy with the Use of the Electromagnetic Field Combined with Light Radiation Emitted by LEDs in the Treatment of Inflammation of the Paranasal Sinuses—A Case Study

Kijak

Cieślar

Kowacka

et al. 2022

IJERPH

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Modern high-resolution volumetric tomography, commonly known as cone beam computed tomography (CBCT), is one of the most innovative imaging techniques which can provide views of anatomical structures not attainable by conventional techniques. Magnetic field LED therapy is a physical therapy method, combining the effects of the Extremely Low Frequency-Electromagnetic Field (ELF-EMF) and high-power light radiation emitted by Light Emitting Diodes (LEDs). The method has been widely applied in the treatment and rehabilitation of complications of many medical conditions, including in dentistry. The aim of this study was to use CBCT to assess the effectiveness of the simultaneous use of electromagnetic field and LED light in the physical therapy of paranasal sinusitis. Treatments employing the electromagnetic field combined with LED light were administered to a 39-year-old female outpatient of the physiotherapy ward for rehabilitation therapy of paranasal sinusitis. Normal sinus pneumatization was restored almost completely. Reduction in the swelling of the sinus mucosa was so significant that even the pneumatization of the ethmoid bulla was restored. Physical therapy with the simultaneous use of ELF-EMF and LED light was found to be effective in the rehabilitation of the patient with paranasal sinusitis. Positive effects of the treatment were confirmed by CBCT findings.

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Photodynamic diagnostics and therapy of premalignant lesions and cancer: a three-year clinical experience

Cited by 3 publications

References 0 publications

The Influence of Magnetic Fields on the Primary Healing of Incisional Wounds in Rats

The Influence of Magnetic Fields on the Primary Healing of Incisional Wounds in Rats

An Insight into the Recent Innovations in Early Detection of Oral Cancer

Cone Beam Computed Tomography in the Assessment of the Effectiveness of Physical Therapy with the Use of the Electromagnetic Field Combined with Light Radiation Emitted by LEDs in the Treatment of Inflammation of the Paranasal Sinuses—A Case Study

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