Photodynamic therapy potential of thiol-stabilized CdTe quantum dot-group 3A phthalocyanine conjugates (QD-Pc)

Tekdaş, Duygu Aydın; Durmuş, Mahmut; Yanık, Hülya; Ahsen, Vefa

doi:10.1016/j.saa.2012.03.036

Cited by 32 publications

(16 citation statements)

References 28 publications

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“…Fluorescence spectrum of CDs showed a 450 nm emission peak under the excitation of 350 nm, with a Stokes shift of 110 nm.It should be noted that when excited at 350 nm, the sodium citrate solution itself was non-emission, suggesting the bright blue fluorescence comes from CDs. When excited at 350 nm, the full width at half maximum of CDs emission spectrum was about 65 nm, which was narrower than those reported elsewhere (>70 nm)[21,[34][35].The quantum yield (Φ u ) of CDs in our experiments was calculated by using quinine sulfate (Φ s =0.55) as the reference standard[36] …”

contrasting

confidence: 56%

Carbon dots as fluorescent probe for “off–on” Detecting sodium dodecyl-benzenesulfonate in aqueous solution

Tao

Liao²,

et al. 2016

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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contrasting

confidence: 56%

Carbon dots as fluorescent probe for “off–on” Detecting sodium dodecyl-benzenesulfonate in aqueous solution

Tao

Liao²,

et al. 2016

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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“…Their characteristic B1 and B2 bands (3)(4)(5)(6)(7)(8)(9)(10) were observed at a range of 313-405 nm (Fig. 1).…”

Section: Syntheses and Characterizationmentioning

confidence: 96%

“…Because of their potential contribution to the next generation of molecular electronic devices such as electrochromic and electro-luminescent displays, nonlinear optics, photovoltaics, chemical sensors nanotechnology, and photosensitizers for photodynamic cancer therapy (PDT) of tumors, studies on the synthesis and characterization of novel phthalocyanines (Pcs) compounds are of considerable interest [1][2][3][4][5][6][7][8][9][10][11]. All the properties of Pcs are influenced and enhanced both by the nature of central metals and the substituent and substituent's position (peripheral or non-peripheral) in the Pc ring.…”

Section: Introductionmentioning

confidence: 99%

Toluene vapor sensing characteristics of novel copper(II), indium(III), mono-lutetium(III) and tin(IV) phthalocyanines substituted with 2,6-dimethoxyphenoxy bioactive moieties

Pişkin

Can

Odabaş

et al. 2018

J. Porphyrins Phthalocyanines

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This study presents the synthesis, characterization and toluene sensing properties of copper(II), indium(III) acetate, mono-lutetium(III) acetate and tin(IV) phthalocyanines substituted with 2,6-dimethoxyphenol bioactive groups at the peripheral and non-peripheral positions. The effects of the substituent's position on the toluene vapor detection capabilities of these compounds were investigated. Adsorption data were analyzed by using first-order and Elovich equations in order to investigate the adsorption kinetics. It was found that the kinetics of the toluene adsorption strongly depends on the position of the substituent groups. Our results showed that the Elovich equation fits the experimental data well for non-peripherally substituted Pc based sensors, while the pseudo first-order model best describes the adsorption data for peripheral substituted Pc based sensors. Some physical, photophysical and photochemical of 2,6-dimethoxyphenoxy substituted metal-free and metallophthalocyanines (indium(III) and zinc(II) Pcs) were investigated by our group [26]. We wondered how copper(II), indium(III), mono-lutetium(III) and tin(IV) Pcs substituted with 2,6-dimethoxyphenoxy bioactive moieties affect the physical, electronic and toluene sensing properties. Hence, highly soluble peripherally and non-peripherally substituted Cu(II), In(III), Lu(III) and Sn(IV) Pcs with 2,6-dimethoxyphenoxy were also synthesized (Scheme 1), and the effects of the position of the substituents and the variety of central metal ions on the their spectroscopic and toluene vapors sensing properties were investigated in this study. KEYWORDS EXPERIMENTAL Materials and Equipment2,6-Dimethoxy-phenoxy substituted phthalonitriles (1 and 2) were obtained by the reaction of 2,6-dimethoxy phenol with 3-nitrophthalonitrile or 4-nitrophthalonitrile through base catalyzed nucleophilic aromatic displacement reaction [26]. All other starting materials and solvents used were obtained commercially. All reactions were carried out under dry nitrogen atmosphere. The novel Pcs (3-10) were successively cleaned by washing with hot acetic acid-water solution by volume 7/3, water, ethanol and acetonitrile in the Soxhlet apparatus. Column chromatography was performed on silica gel 60 for a proper purification of the raw compounds. The purity of the products was tested in each step by thin layer chromotography (Silicagel F-254 coated TLC plate). Melting points of the Pc compounds were found to be higher than 300 °C. IR Spectra and electronic spectra were recorded on a Shimadzu FTIR-8300 (ATR) and a Shimadzu UV-1601 spectrophotometer, respectively. Elemental analyses were performed by the Instrumental Analysis Laboratory of TUBITAK-Ankara. Mass spectra were acquired on a Microflex III MALDI-TOF mass spectrometer (Bruker Daltonics, Germany) equipped with a nitrogen UV-Laser operating at 337 nm in reflectron mode with an average of 50 shots. SynthesisGeneral procedure for the synthesis of metallophth alocyanines (3-10).

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“…In the particular case of FRETQDs studies, a broad absorption band combined with a size-tunable fluorescence and larger physical size (when compared to conventional dyes) allow: (i) optimization of the spectral overlap with any potential FRET acceptor; (ii) excitation at a wavelength far from the acceptor absorption peak (minimizing acceptor direct excitation); QDs can be excited over a range of wavelengths in the blue-ultraviolet region of the spectrum to allow minimization of the direct excitation of acceptors and (iii) the ability to assemble multiple acceptors around a QD core to increase the overall FRET efficiency (Algar & Krull, 2008;Bakalova et al, 2004;Juzenasa et al, 2008;Medintz & Mattoussi, 2009;Tekdas et al, 2012). The use of fluorescence resonance energy transfer (FRET) as a mechanism of tuning QDs' fluorescence is particularly advantageous and due to their high photostability QDs are ideal donors (Algar & Krull, 2008;Bakalova et al, 2004;Medintz & Mattoussi, 2009).…”

Section: Quantum Dots As Probes In Other Bioassaysmentioning

confidence: 99%

Quantum Dots in Biomedical Research

Fontes¹,

Lira²,

Seabra³

et al. 2012

Biomedical Engineering - Technical Applications in Medicine

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Photodynamic therapy potential of thiol-stabilized CdTe quantum dot-group 3A phthalocyanine conjugates (QD-Pc)

Cited by 32 publications

References 28 publications

Carbon dots as fluorescent probe for “off–on” Detecting sodium dodecyl-benzenesulfonate in aqueous solution

Carbon dots as fluorescent probe for “off–on” Detecting sodium dodecyl-benzenesulfonate in aqueous solution

Toluene vapor sensing characteristics of novel copper(II), indium(III), mono-lutetium(III) and tin(IV) phthalocyanines substituted with 2,6-dimethoxyphenoxy bioactive moieties

Quantum Dots in Biomedical Research

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