Photoelectric effect driving PANI/PB multicolor visualized detection of CEA based on Ag2S NPs@ZnO NTs

Reagentless and sensitive determination of carcinoembryonic antigen based on a stable Prussian blue modified electrode

“…Comparison between detection of CEA using different immunosensor is provided in Table S1. † The LOD is lower than those obtained using Ab/Ag 2 S@ZnO/AuNPs, 26 Ab/chitosan-AuNPs/GCE, 27 Ab/chitosan glutaraldehyde, 28 TiO 2 -AuNPscarbon paste electrode, 29 or Ab/AuNPs/Au electrode, 30 but higher than that obtained from Ab/Ag-Co 3 O 4 @N-doped graphene oxide/GCE, 31 or Ab/polyethyleneimine/AuNPs@Naon/ K 3 Fe(CN) 6 @chitosan/GCE. 32 In comparison with other technologies, our electrochemical sensing is attractive because of high sensitivity, no need of bulky instrumentation and easy operation.…”

Recent Advances in Nanomaterial‐based Optical Biosensors as Potential Point‐of‐Care Testing (PoCT) Probes in Carcinoembryonic Antigen Detection

“…With such a mechanism, the electron flow efficiency is guaranteed. Furthermore, the charge recombination is reduced that accompanied by a higher intensity resolution [73a,82a, 84] . Despite an inorganic‐based biosensor, colorimetric biosensor can also be an organic‐derived one by involving organic substrate such as nematic LC 4‐cyano‐4′‐pentylbiphenyl (5CB), [78b] and glutaraldehyde [85] .…”

“…The selectivity of the sensing probe can be achieved by having the antigen‐antibody immunoassay [73a,77–78,80a–c,82a,83–86] or aptamer‐labelled biosensor [78d,79,80d,81] . Nevertheless, the labelled free system [78d,85] is suggested to overcome the shortcoming of labelled one as aptasensor that utilises the single‐stranded oligonucleotides chain as biorecognition site with an improved affinity towards analyte.…”

“…Nevertheless, the antibody is immobilised on the surface of Ag 2 S NPs @ ZnO NTs that coated with AuNPs. This is simply possible due to the existence of Au−NH 2 ‐bond [73a] …”

Electrochemistry/Photoelectrochemistry-Based Immunosensing and Aptasensing of Carcinoembryonic Antigen

“…Moreover, the design of new detection modes will inject fresh vitality into the further development of photoelectrochemical sensing devices. Based on this, Wang et al developed a photoelectric effect-driven multicolor visualized immunosensing platform using anti-CEA/Au NPs/Ag 2 S NPs@ZnO nanotubes (NTs)/FTO as photoelectrode and polyaniline/Prussian blue (PANI/PB) bilayer films as indicator electrodes [108]. Under light irradiation, the photoexcited Ag 2 S NPs@ZnO NTs generated electron-hole pairs in which photoelectrons and holes could migrate to reduce PB and oxidize PANI, respectively, enabling the multicolor transition of PANI/PB.…”