“…1), i.e., the generation of excited electrons in PEC active materials, introduction of specific materials for the formation of new electron transfer pathways, and the separation of excited electrons in semiconductors. Although there are some excellent reviews about PEC sensing from other perspectives, such as, architectures of PEC biosensing, 11,48,49 summary of signal amplification strategies, 50,51 PEC active materials 17,52,53 or application of PEC biosensors, 54,55 to our knowledge, systematically summarizing the construction mechanism of PEC biosensors from the perspective of the electron transfer process has not been reported yet. We hope this review will enhance the interest of readers leading to further development of PEC biosensing.…”