Phototherapy in the neonatal intensive care unit – quantity and quality

Maisels, M. Jeffrey

doi:10.1111/apa.14241

Cited by 8 publications

(5 citation statements)

References 18 publications

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“…Continuous irradiation is mostly used clinically, however, there are documents showing that a long irradiation time can cause many adverse reactions (13). According to the research by Maisels (14), reducing the duration of phototherapy can decrease the adverse reactions caused by phototherapy and helps the nurse care and treatment of children. Therefore, this study retrospectively analyzed neonatal ABO hemolytic jaundice in Qilu Hospital of Shandong University (Qingdao, China) for continuous and intermittent blue light irradiation.…”

Section: Introductionmentioning

confidence: 99%

Analysis of therapeutic effect of intermittent and continuous phototherapy on neonatal hemolytic jaundice

Zhou

et al. 2019

Exp Ther Med

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Clinical efficacy and adverse reaction rates of ABO hemolytic jaundice in patients with continuous and intermittent blue light irradiation were compared, to provide reference for clinical treatment of neonatal ABO hemolytic jaundice. A retrospective analysis of 307 patients with neonatal hemolytic jaundice admitted to Qilu Hospital of Shandong University (Qingdao) from January 2010 to December 2017 was undertaken. A total of 165 cases of children with continuous blue light irradiation and 142 cases of intermittent blue light irradiation were analyzed. Also the serum bilirubin levels, phototherapy time and frequency, treatment efficiency and adverse reaction rates were compared between the groups. The phototherapy time of children in the continuous phototherapy group was significantly higher from the intermittent phototherapy group, and the difference was statistically significant (t=26.800, P<0.001). Before treatment, there was no significant difference in serum bilirubin levels between continuous and intermittent phototherapy groups (P>0.050). Serum bilirubin levels of patients in continuous and intermittent phototherapy groups were lower than both previous and before treatment period, and differences were statistically significant (P<0.001). The overall effective rate of the continuous phototherapy group was higher than that of the intermittent phototherapy group (P>0.050). The adverse reaction rates after treatment in the continuous phototherapy group was significantly higher than the intermittent phototherapy group (P<0.050). After the symptomatic treatment in children, the adverse reactions ceased. The therapeutic effect of intermittent blue light irradiation on neonatal ABO hemolytic jaundice was consistent with the continuous blue light irradiation treatment, and the intermittent blue light irradiation treatment has a low adverse reaction rate, and is worth promotion in clinical practice.

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Section: Introductionmentioning

confidence: 99%

Analysis of therapeutic effect of intermittent and continuous phototherapy on neonatal hemolytic jaundice

Zhou

et al. 2019

Exp Ther Med

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“…Phototherapy is a kind of proven and standard treatment for most neonates with hyperbilirubinemia, which could help avoiding bilirubin-induced neurological dysfunctions including acute bilirubin encephalopathy and kernicterus, but it is recommended to use phototherapy for the shortest possible time because of potential side effects of phototherapy for newborns [ 16 , 17 ]. In our study, there were no significant differences in the duration of phototherapy and hospitalization periods between the two groups.…”

Section: Discussionmentioning

confidence: 99%

Intravenous immunoglobulin G in the treatment of ABO hemolytic disease of the newborn during the early neonatal period at a tertiary academic hospital: a retrospective study

et al. 2021

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Objective To evaluate the efficacy and safety of intravenous immunoglobulin G (IVIG) in infants with ABO hemolytic disease of the newborn (HDN). Methods Infants with moderate-to-severe ABO HDN during early neonatal period (<7 days) at our hospital in 2017 were included in this retrospective study. Patients treated with IVIG and phototherapy were classified as the IVIG group, and those who only received phototherapy were classified as the phototherapy only group. Results Forty-six patients were classified into the IVIG group and 68 other patients were classified into the phototherapy only group. There was no significant difference in duration of phototherapy, hospitalization periods, needs for exchange transfusion, transfusions, and incidence of bilirubin-induced neurological sequelae between these two groups (P = 0.20, 0.27, 0.65, 0.47, 0.78, respectively). Conclusion It seems unnecessary to expose neonates to IVIG in moderate-to-severe ABO HDN when the available data show no appreciable benefits.

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“…Researchers (Hodgman, 1976) compared intermittent with continuous phototherapy and discovered that continuous phototherapy played a more effective role but was related to more metabolic needs. Maisels's research showed (Maisels, 2018) that a shorter duration of phototherapy could reduce the side effect caused by phototherapy and support the nurse care and treatment of children. Therefore, infants could be subjected to the least amount of irradiation without sacrificing the overall efficiency of the treatment for neonatal hyperbilirubinaemia.…”

Section: Backg Rou N Dmentioning

confidence: 99%

Efficacy of Intermittent Phototherapy versus Continuous Phototherapy for Treatment of Neonatal Hyperbilirubinaemia: A Systematic Review and Meta‐analysis

Chu

Xue

Qiao

2020

Journal of Advanced Nursing

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Aims We review the current literatures to determine whether intermittent phototherapy is more effective than continuous phototherapy in treating neonatal hyperbilirubinaemia. Design The systematic review is a systematic review and meta‐analysis. The Preferred Reporting Items for Systematic Reviews and Meta‐analyses (PRISMA) guidelines were used for reporting methods and results of synthesis with meta‐analysis. Synthesis Without Meta‐analysis (SWIM) guidelines were used for reporting methods and results of synthesis without meta‐analysis. Data Source Pubmed, Embase, Cochrane library, China National Knowledge Infrastructure, China Biology Medicine, VIP Database, and Wanfang Database. Review methods PICOS eligibility criteria were used to select original studies published from 1984 through 2019. Data were statistically extracted and evaluated using RevMan 5.3 software. Results A total of 416 records were identified through database searching. Four studies (three randomized studies and one retrospective study) meet the final inclusion criteria. Seven hundred and sixteen neonates were included in the meta‐analysis. There was no difference in the treatment efficacy and total serum bilirubin (TSB), while there was a significant difference in phototherapy duration and side effects after treatment of intermittent phototherapy and continuous phototherapy for neonatal hyperbilirubinaemia. Conclusion Intermittent phototherapy appeared to be as effective as continuous phototherapy for the treatment of neonatal hyperbilirubinaemia and is safer than continuous phototherapy. Healthcare organizations and health workers should choose intermittent phototherapy as the preferred therapy for neonatal hyperbilirubinaemia. Impact Intermittent phototherapy is an effective, feasible, and safer treatment method for the infants with hyperbilirubinaemia in paediatric department. Healthcare organizations and health workers should choose intermittent phototherapy as the preferred therapy for neonatal hyperbilirubinaemia.

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Phototherapy in the neonatal intensive care unit – quantity and quality

Cited by 8 publications

References 18 publications

Analysis of therapeutic effect of intermittent and continuous phototherapy on neonatal hemolytic jaundice

Analysis of therapeutic effect of intermittent and continuous phototherapy on neonatal hemolytic jaundice

Intravenous immunoglobulin G in the treatment of ABO hemolytic disease of the newborn during the early neonatal period at a tertiary academic hospital: a retrospective study

Efficacy of Intermittent Phototherapy versus Continuous Phototherapy for Treatment of Neonatal Hyperbilirubinaemia: A Systematic Review and Meta‐analysis

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