2018
DOI: 10.1016/j.virusres.2017.10.004
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Phylogenetic analysis of Human papillomavirus 16 variants isolated from Indian Breast cancer patients showed difference in genetic diversity with that of cervical cancer isolates

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Cited by 6 publications
(11 citation statements)
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“…The HPV screening and their genetic diversity in clinical settings could be an important factor for molecular diagnostic and vaccination strategies (Li et al, 2011). Globally, the prevalence and genetic diversity of HPVs, especially HPV16 and HPV18 have been reported by various research groups and published in many reports (Assoumou et al, 2015, Wilting and Steenbergen, 2016, El-Aliani et al, 2017, Xi et al, 2017, Basto et al, 2017, Doorslaer et al, 2017, Islam et al, 2018, Xu et al, 2018, Van der Weele et al, 2018). Recently, HPV infection in females with normal cervical cytology and their genotyping with phylogenetic tree was performed by PCR in total 1011 patients in Pakistan and found that 4.74% HPV prevalence with HPV6 (in 25% of infected individuals), followed by HPV55 (22.9%), HPV11 (20.8%), and high-risk types HPV45 (12.5%), HPV33 (8.33%), HPV18 (6.25%), and HPV16 (4.16%).…”
Section: Discussionmentioning
confidence: 99%
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“…The HPV screening and their genetic diversity in clinical settings could be an important factor for molecular diagnostic and vaccination strategies (Li et al, 2011). Globally, the prevalence and genetic diversity of HPVs, especially HPV16 and HPV18 have been reported by various research groups and published in many reports (Assoumou et al, 2015, Wilting and Steenbergen, 2016, El-Aliani et al, 2017, Xi et al, 2017, Basto et al, 2017, Doorslaer et al, 2017, Islam et al, 2018, Xu et al, 2018, Van der Weele et al, 2018). Recently, HPV infection in females with normal cervical cytology and their genotyping with phylogenetic tree was performed by PCR in total 1011 patients in Pakistan and found that 4.74% HPV prevalence with HPV6 (in 25% of infected individuals), followed by HPV55 (22.9%), HPV11 (20.8%), and high-risk types HPV45 (12.5%), HPV33 (8.33%), HPV18 (6.25%), and HPV16 (4.16%).…”
Section: Discussionmentioning
confidence: 99%
“…The viral genome size range from ∼7.9–8.0 kb in length containing six early genes (E1, E2, E4, E5, E6 and E7) and 2 late genes designated as L1, L2 (Doorbar et al, 2012, Van Doorslaer et al, 2013, El-Aliani et al, 2017, Van der Weele et al, 2018). Currently, approximately 200 HPVs genotypes have been identified and divided based on more than 10% nucleotide diversity of L1 gene (Van Doorslaer et al, 2013, Ervik et al, 2016, Basto et al, 2017, Islam et al, 2018). Based on criteria defined by the International Agency for Research on Cancer, the development of cervical cancer is predominantly reported to be caused by fifteen high-risk HPVs (hrHPV) (IARC, 2012).…”
Section: Introductionmentioning
confidence: 99%
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“…The four major HPV16 variant lineages are European-Asian (EAS), African-1 (AFR-1), African-2 (AFR-2) and North-American/Asian-American (NA/AA). The European variant lineage is further arranged into several variant sublineages [ 10 , 11 ]. Diverse HPV16 variants have in studies shown to contribute to the development of cervical cancer and precancerous lesions to different degrees [ 12 14 ].…”
Section: Introductionmentioning
confidence: 99%