Phylogenetic analysis of Newcastle disease viruses isolated from waterfowl in the Upper Midwest Region of the United States

Jindal, Naresh; Chander, Yogesh; Chockalingam, Ashok; Abin, Martha; Redig, Patrick T.; Goyal, Sagar M.

doi:10.1186/1743-422x-6-191

Cited by 53 publications

(48 citation statements)

References 31 publications

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“…Virulent NDV is an important pathogen in poultry and is characterized by the addition of basic amino acids at the fusion protein cleavage site (Collins et al, 1993). In waterfowl NDV isolates usually have fusion protein cleavage sites consistent with avirulent NDV (Jindal et al, 2009). Our fusion cleavage site analysis supports this.…”

Section: Discussionsupporting

confidence: 72%

Wood ducks (Aix sponsa) as potential reservoirs for avian influenza and avian paramyxoviruses

et al. 2015

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Influenza A viruses (IAVs) and avian paramyxoviruses (APMVs) are important pathogens of poultry worldwide, and both commonly occur in wild waterfowl, especially ducks in the family Anatidae. Although wood ducks (Aix sponsa) are members of the Anatidae, their behaviour differs from most other species in this family, which could affect the transmission of IAVs and APMVs. We collected cloacal and oropharyngeal swab and blood samples from more than 700 wood ducks across nine states in the eastern United States of America. No IAVs were isolated, and based on blocking enzyme-linked immunoassay ELISA results, antibodies to IAVs were only detected in 0.2% of samples. In contrast, 23 (3%) APMVs were isolated (22 Newcastle disease virus and 1 APMV-6), and antibodies to multiple serotypes of APMVs were detected in more than 60% of the samples. After-hatch-year birds were more likely to be antibody positive for APMV-4 and APMV-6 compared to hatch-year birds. Female birds were more likely to be antibody positive for APMV-4 than were male birds. Our results indicate that wood ducks are probably not an important host for IAV but are frequently infected with APMVs.

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Section: Discussionsupporting

confidence: 72%

Wood ducks (Aix sponsa) as potential reservoirs for avian influenza and avian paramyxoviruses

et al. 2015

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“…There is increasing evidence that wild waterbirds are natural carriers of avirulent class I and class II genotype I and X strains (21)(22)(23)(24)(25). It was thus not surprising to find five out of nine positive samples from waterbirds, including three avirulent genotype I strains in ducks, in our study.…”

Section: Discussionmentioning

confidence: 63%

Characterization of Newcastle Disease Viruses in Wild and Domestic Birds in Luxembourg from 2006 to 2008

Snoeck

Marinelli

Charpentier

et al. 2013

Appl Environ Microbiol

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“…The most commonly isolated ''extraneous'' virus in AIV surveillance studies is NDV, whose presence in cloacal samples may hinder the isolation of AIV. 7,11,12 This suppression of AIV by NDV could jeopardize valuable information needed for AIV ecology and epidemiology. In the present proof-of-concept study, it was demonstrated that pretreatment of such samples with anti-NDV antiserum overcomes this problem in many cases.…”

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confidence: 99%

Selective Isolation of Avian Influenza Virus (AIV) from Cloacal Samples Containing AIV and Newcastle Disease Virus

et al. 2011

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Abstract. Avian influenza viruses (AIVs) are important zoonotic pathogens whose natural reservoir is waterfowl. In addition to AIV, waterfowl are often coinfected with other viruses, such as the paramyxoviruses, of which Newcastle disease virus (NDV) is of particular importance because of the highly virulent nature of certain strains of this virus for domestic poultry. In routine surveillance of waterfowl for AIV, a number of cloacal samples were encountered that were positive for AIV by real-time reverse transcription polymerase chain reaction (RT-PCR), but did not yield AIV by inoculation in embryonated chicken eggs. On further testing, these samples were also positive for NDV by conventional RT-PCR. It was hypothesized that if both NDV and AIV are present in a sample, the former may overgrow AIV yielding false-negative AIV results. Such samples were treated with chicken anti-NDV polyclonal antiserum and then inoculated in embryonated chicken eggs. Several samples were found to be positive for different subtypes of AIV, indicating that, in the presence of mixed infection with NDV and AIV, it is imperative to remove the influence of NDV, so a true picture of AIV prevalence emerges. An additional benefit is that information on the circulation of NDV in these birds sheds light on their epidemiologic and ecologic significance.

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Phylogenetic analysis of Newcastle disease viruses isolated from waterfowl in the Upper Midwest Region of the United States

Abstract: We conclude that more than one genotype of NDV circulates in waterfowl in the Upper Midwest region of the US. Continuous surveillance may help better understand the epidemiology of NDVs maintained in wild bird populations and their relationship to NDVs in domestic poultry, if any.

Cited by 53 publications

References 31 publications

Wood ducks (Aix sponsa) as potential reservoirs for avian influenza and avian paramyxoviruses

Wood ducks (Aix sponsa) as potential reservoirs for avian influenza and avian paramyxoviruses

Characterization of Newcastle Disease Viruses in Wild and Domestic Birds in Luxembourg from 2006 to 2008

Selective Isolation of Avian Influenza Virus (AIV) from Cloacal Samples Containing AIV and Newcastle Disease Virus

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