Phylogeny of bovine norovirus in Egypt based on VP2 gene

Mohamed, Fakry F.; Ktob, Gamelat K.F.; Ismaeil, Mohamed; Ali, Ahmed; Goyal, Sagar M.

doi:10.1016/j.ijvsm.2018.04.005

Cited by 4 publications

(3 citation statements)

References 23 publications

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“…3b). Comparing the VP1 structures of the Xinjiang strains with the VP1 structure of GⅢ.1 BNoV, there were significant differences in the P2 subdomain, which also verified the finding of a previous study (23) that the NoV genetic variation can cause differences in the P2 subdomain. (Fig.…”

Section: Epidemiological Survey Of Bnov In Xinjiangsupporting

confidence: 89%

The first complete genome sequence and genetic evolution analysis of bovine norovirus in Xinjiang, China

Ma,

Jiang,

Quan

et al. 2024

Journal of Veterinary Research

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Introduction Viruses are among the main pathogens causing diarrhoea in calves. The current study found that bovine norovirus (BNoV) is one of the principal viruses causing diarrhoea in calves in Xinjiang, China. Material and Methods A total of 974 calf faecal samples from six regions in Xinjiang were tested for BNoV using reverse-transcriptase PCR. The genomic characteristics of BNoV and the genetic evolution of the VP1 gene, protein three-dimensional structure characteristics and amino acid variation were analysed using bioinformatics methods. Results Epidemiological survey results showed that the infection rate of BNoV was 19.82%, and all samples tested positive in five regions. The results of the genetic evolution analysis showed that BNoV strains from Tacheng of northern Xinjiang and Kashgar of southern Xinjiang both belonged to the GIII.2 genotype of BNoV but were not on the same cluster of evolutionary branches. Additionally, the amino acid variation of the VP1 protein was not observed to significantly affect its spatial structure. Conclusion This study is the first to report the genetic characteristics of the BNoV complete genome sequence in Xinjiang and provides a scientific basis for BNoV vaccine development and pathogenesis research.

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Section: Epidemiological Survey Of Bnov In Xinjiangsupporting

confidence: 89%

The first complete genome sequence and genetic evolution analysis of bovine norovirus in Xinjiang, China

Ma,

Jiang,

Quan

et al. 2024

Journal of Veterinary Research

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“…Recently, an updated classification of norovirus genogroups and genotypes was published (Chhabra et al., 2019); however, this update was focused on human norovirus. On the other hand, several studies have been recently performed in order to characterize norovirus circulating in cattle (Castells et al., 2020; Guo et al., 2018; Karayel‐Hacioglu & Alkan, 2019; Mohamed et al., 2017, 2018; Pourasgari et al., 2018; Ryu et al., 2020; Shi et al., 2019; Symes et al., 2018; Turan et al., 2018; Wang et al., 2019 ). A timely, exhaustive, and complete classification of GIII noroviruses is clearly needed, and in this work, we fill this need.…”

Section: Discussionmentioning

confidence: 99%

Evolutionary history and spatiotemporal dynamic of GIII norovirus: From emergence to classification in four genotypes

Castells

Cristina

Colina

2021

Transbounding Emerging Dis

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Noroviruses belong to a genetically diverse group of viruses infecting a wide range of mammalian host species, and those detected in cattle and sheep are classified within genogroup III (GIII). The current classification of norovirus in genogroups and genotypes is based on phylogenetic clustering and average distances within and between these phylogenetic clusters; however, the classification studies have been focused mainly on human norovirus, being GIII norovirus relegated. Due to the increasing number of studies on GIII norovirus, the need of an updated and extensive classification is evident. The aim of this study was to update the classification of norovirus within GIII, to describe the emergence of a circulating recombinant strain, and to reconstruct the evolutionary history of this genogroup. Two P‐types (GIII.P1–2) and four genotypes (GIII.1–4) were described. For the genogroup GIII, the evolutionary rate estimated was 2.78E‐3 s/s/y (95%HPD, 1.79E‐3 s/s/y–3.78E‐3 s/s/y), and the tMRCA was estimated around 1500 (95%HPD, 1247–1688). Despite the long history of this genogroup, the genotypes detected at present emerged in the last 100 years. Interestingly, most of the recombinant GIII.2P[1] strains detected worldwide were originated from a single recombination event and this recombinant strain was later dispersed through the world. Finally, our results indicate that a scenario of genotypes replacement through the time is highly probable.

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“…Different sequence insertions and deletions were also observed in VP2 compared with GIII.1, GIII.2 and GIII.3. While the precise role of VP2 remains to be elucidated, there is evidence that it might be involved in particle stabilization [47,48]. Therefore, whether these sequence variations could affect the stability of NoV particles also needs to be further investigated.…”

Section: Sequence Characteristics In the Vp1 And Vp2 Domains Of Smu-yak-j1mentioning

confidence: 99%

First Detection and Genomic Characterization of Bovine Norovirus from Yak

et al. 2022

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Yak are a unique free-grazing bovine species in high-altitude areas. The objective of this study was to investigate the presence and molecular characteristics of BNoV in yak. A total of 205 diarrheal samples of yak (aged ≤ 3 months) were collected from 10 farms in Sichuan Province, China, from May 2018 to October 2020, and four samples were detected as BNoV-positive with RT-PCR. Moreover, a nearly full-length genome of SMU-YAK-J1 containing three complete ORFs was successfully sequenced. Sequence analysis with only nine genome sequences of the GIII genogroup showed that SMU-YAK-J1 was most closely related with GIII.P2 GIII.4, sharing 90.9% gnomic nucleotide identity, but only shared 71.6–85.9% with other genotypes, which confirmed that SMU-YAK-J1 belongs to genotype GIII.P2 GIII.4. However, compared with the sole genome of GIII.4 in GenBank, the BNoV in this study also exhibited many unique amino acid changes among all the three ORFs, which may represent the unique genetic evolution of BNoV in yak. This study first determined the presence of BNoV in yak, contributing to a better understanding of the prevalence and genetic evolution of BNoV.

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Phylogeny of bovine norovirus in Egypt based on VP2 gene

Cited by 4 publications

References 23 publications

The first complete genome sequence and genetic evolution analysis of bovine norovirus in Xinjiang, China

The first complete genome sequence and genetic evolution analysis of bovine norovirus in Xinjiang, China

Evolutionary history and spatiotemporal dynamic of GIII norovirus: From emergence to classification in four genotypes

First Detection and Genomic Characterization of Bovine Norovirus from Yak

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