Physical Activity, Blood Pressure, and Cardiac Structure and Function

Kokkinos, Peter; Narayan, Puneet; Pittaras, Andreas

doi:10.1007/978-3-030-04816-7_10

Cited by 1 publication

(2 citation statements)

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“…In HFrEF, minor changes were expected, because cardiac dysfunction is the main factor limiting improvements in VO 2peak . In this sense, increases in CRF between ~0.29 and 0.57 METs (1-2 mL•kg −1 •min −1 ) positively impact on mortality and hospitalizations in HFrEF [28,29]. In our study, an increase of 0.7 METs (~2.5 mL•kg −1 •min −1 ) from baseline was observed in HFrEF after 29.8 (4.5) average days of exercise sessions.…”

Section: Discussionsupporting

confidence: 54%

“…Currently, one of the most promising submaximal indexes obtained from CPET is VE•VCO 2 −1 slope , which represents ventilatory efficiency during submaximal effort, which may be elevated by an increased air dead-space, chemoreceptors numbers, peripheral ergoreceptor activity, and active skeletal muscle mass [42]. Although the HFrEF (32.0 ± 6.7, data not shown) group improved ventilatory efficiency (decreased < 34), this improvement did not reach normal values (25)(26)(27)(28)(29)(30) [40]. However, a value lower than 32.9 is associated with a good prognosis in these patients [42].…”

Section: Discussionmentioning

confidence: 97%

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Average and Interindividual Effects to a Comprehensive Cardiovascular Rehabilitation Program

Tuesta

Álvarez

Pedemonte

et al. 2022

IJERPH

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Background: To describe the average effects and the interindividual variability after a comprehensive outpatient cardiovascular rehabilitation (CCR) program using concurrent exercise training prescribed according to cardiovascular risk stratification on cardiorespiratory fitness (CRF), anthropometric/body composition, quality of life and emotional health in patients of four cardiovascular disease profiles. Methods: CRF, anthropometric/body composition, quality of life, and emotional health were measured before and after a CCR and analyzed in heart valve surgery (HVS), heart failure with reduced ejection fraction (HFrEF), post-acute myocardial infarction (post-AMI), and in coronary artery disease (CAD) patients. Twenty, twenty-four, and thirty-two exercise sessions were prescribed according to mild, moderate, and severe baseline cardiovascular risk, respectively. In addition to concurrent exercise training, nutritional counseling, psychological support, and lifestyle education programs were performed. Results: The main outcomes by delta changes comparisons (Δ) revealed no significant differences at anthropometric/body composition as ΔBody fat decreases (HVS Δ−1.1, HFrEF Δ−1.0, post-AMI Δ−1.4, CAD Δ−1.2 kg) and ΔSkeletal muscle mass increases (HVS Δ+1.4, HFrEF Δ+0.8, post-AMI Δ+0.9, CAD Δ+0.9 kg), and CRF performance as ΔVO2peak increases (HVS Δ+4.3, HFrEF Δ+4.8, post-AMI Δ+4.1, CAD Δ+5.1 mL/kg/min) outcomes among HVS, HFrEF, post-AMI, and CAD (p > 0.05). Secondary outcomes showed significant pre-post delta changes in METs (HVS Δ+1.8, HFrEF Δ+0.7, post-AMI Δ+1.4, CAD Δ+1.4), and maximal O2pulse (HVS Δ+3.1, post-AMI Δ+2.1, CAD Δ+1.9). In addition, quality of life had a significant improvement in physical functioning (HVS Δ+17.0, HFrEF Δ+12.1, post-AMI Δ+9.8, CAD Δ+11.2), physical role (HVS Δ+28.4, HFrEF Δ+26.8, post-AMI Δ+25.6, CAD Δ+25.3), vitality (HVS Δ+18.4, HFrEF Δ+14.3, post-AMI Δ+14.2, CAD Δ+10.6) and social functioning (HVS Δ+20.4, HFrEF Δ+25.3, post-AMI Δ+20.4, CAD Δ+14.8) in all cardiovascular disease. For anxiety (HVS Δ−3.6, HFrEF Δ−2.3, post-AMI Δ−3.0, CAD Δ−3.1) and depression (HVS Δ−2.8, HFrEF Δ−3.4, post-AMI Δ−3.2, CAD Δ−2.3) significant changes were also observed. Conclusions: A CCR program that prescribes the number of exercise sessions using a cardiovascular risk stratification improves CRF, QoL, and emotional health, and the average results show a wide interindividual variability (~25% of non-responders) in this sample of four CVD profile of patients.

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Section: Discussionsupporting

confidence: 54%