The article is devoted to computer modeling in the problems of ensuring the safety of production processes in the organization of radio-electronic and instrument-making industries under the influence of damaging factors of emergency situations. The organization of any production is associated with the establishment of a number of technological processes, both basic and related. Ensuring safety and sustainability are one of the important accompanying processes of radio-electronic and instrument-making industries. At present, these processes are coming to the fore, especially when it becomes relevant to establish production in the conditions of predicted emergencies. Manufactured products-radio-electronic devices must also meet the requirements of thermal, radiation and mechanical resistance. If you do not take into account the risk factors of failure of devices and electronic components, then even a small deviation of the environmental parameters from normal values will lead to a man-made accident. This is especially true for devices operating under conditions of ionizing radiation, large temperature differences, and mechanical influences.