Physico-chemical solid-state characterization of omeprazole sodium: Thermal, spectroscopic and crystallinity studies

Synthesis of 99mTc-labeled 2-Mercaptobenzimidazole as a novel radiotracer to diagnose tumor hypoxia

“…HRMS (ESI): m/z [M + H + ] calculated for C 7 H 6 N 2 S: 151.0324, found: 151.0327 (M = 100%). The crystallinity of the final product was characterized by X-ray powder diffraction (XRPD) analysis with major peaks at position 14.84, 23.61, 28.46, 32.28 and 43.52 2(θ) degree which is similar to the spectrum reported in literature [ 34 , 35 ] (see ESI, Fig. S3).…”

Polymorphism and Solvatomorphism 2009

“…A variety of methods were used to study the degrees of crystallinity associated with omeprazole sodium, its dehydration product, and its free base. 116 The water molecules in the monohydrate were noted to be hydrogen bonded to the imidazol ring nitrogen and the sulfoxide groups, and desolvation of this monohydrate yielded an amorphous form. The consequences of these trends were discussed in context of a preformulation program.…”

Thermal analysis as a screening technique for the characterization of babassu flour and its solid fractions after acid and enzymatic hydrolysis

“…The non-isothermal Ozawa method was applied in this study, which is an integral method for determining the activation energies from dynamic heating experiments [27,28]. The kinetics data were calculated by plotting mass loss versus temperature for five TG curves obtained at different heating rates.…”