Physico-chemical standardization of Hansraj (Adiantum capillus-Veneris)

Abstract

Ethno-botanical use and traditional knowledge of plants have been usually recognized all over the world. The outstanding characteristics of extracts obtained from this drug have been technically studied, attributing the main biological activity to its tannin and flavonoid content. Recent study about this drug Adiantum capillus-veneris Linn requires pharmacognostical evidences to develop quality-control methods for raw materials and extracts produced with this plant drug. In this research article macro and micro-scopic studies were proven the authentication of the real drug in which adulteration is allowed in commercial samples of this plant material. The parameters which were mention in this study all are according to WHO guidelines and Indian Pharmacopoeia (IP). The morphological characteristics present in this article can be useful for quick identification of the drug, particularly useful in the case of powdered drug. Physicochemical parameters such as total ash, water soluble ash, acid insoluble ash, loss on drying, percentage of foreign matter and extractive values were determined. Preliminary phytochemical screening in different solvents showed the presence of flavonoids, terpenoids, fats, tannins and phenolic compounds. The various phytochemicals presence in the drug are confirmed by thin layer chromatography (TLC) profile. The study can serve as a valuable source of information and provide suitable standards for the presence of various phytochemicals. The results extracted from this study such as identification, phytochemical investigation etc. could be helpful in future research and uses

Evaluation of safety of aqueous extract of Tapinanthus sessillifolius parasitic on Psidium guava

“…The repeated administration of doses up to 800 mg/kg to normal rats did not produce observable toxic effects at the doses tested. This is consistent with other reports which showed that mistletoes extracts are relatively non-toxic [30,31,32]. However, in handling the plant material from raw material to extract, physicochemical reference like moisture and ash are critical so as to avoid deterioration, microbial and fungal growth that can be introduced as toxicants [33].…”

The Antiproliferative Activity of Adiantum pedatum Extract and/or Piceatannol in Phenylhydrazine-Induced Colon Cancer in Male Albino Rats: The miR-145 Expression of the PI-3K/Akt/p53 and Oct4/Sox2/Nanog Pathways

“…The components were identified by comparing their retention times and mass spectra to the databases Wiley 09 and NIST 11 [ 121 ]. Assays for the AP moisture content%, pH, cold extract%, hot extract%, ash (total, acid insoluble, and water-soluble ash%), and total phenolic compound% and tests for saponins, tannin, flavonoids, and proteins were performed according to the method described in [ 122 ], as shown in Table 4 .…”

Test

“…Whenever the quality assurance entity had also identifying of drug, adulterants, substitutes, and assay of active chemical constituent of greater importance of speci ic plant then they would be termed just like phamacopeial level of quality regulation. It is really is predicted upon that various important analysis parameter such as organoleptic characteristics, residue value, water content, bacterial contamination as well as spectroscopic but also chromatographic evaluation [11,12].…”