Ethno-botanical use and traditional knowledge of plants have been usually recognized all over the world. The outstanding characteristics of extracts obtained from this drug have been technically studied, attributing the main biological activity to its tannin and flavonoid content. Recent study about this drug Adiantum capillus-veneris Linn requires pharmacognostical evidences to develop quality-control methods for raw materials and extracts produced with this plant drug. In this research article macro and micro-scopic studies were proven the authentication of the real drug in which adulteration is allowed in commercial samples of this plant material. The parameters which were mention in this study all are according to WHO guidelines and Indian Pharmacopoeia (IP). The morphological characteristics present in this article can be useful for quick identification of the drug, particularly useful in the case of powdered drug. Physicochemical parameters such as total ash, water soluble ash, acid insoluble ash, loss on drying, percentage of foreign matter and extractive values were determined. Preliminary phytochemical screening in different solvents showed the presence of flavonoids, terpenoids, fats, tannins and phenolic compounds. The various phytochemicals presence in the drug are confirmed by thin layer chromatography (TLC) profile. The study can serve as a valuable source of information and provide suitable standards for the presence of various phytochemicals. The results extracted from this study such as identification, phytochemical investigation etc. could be helpful in future research and uses
Hansraj(Adiantum capillus-veneris) is an herbal plant used in Unanisystem of medicine since ancient time. Leaf, roots, stem of the plant are mainly used in the treatment ofkidney stone, diabetes, fungal infection, thyroid and respiratory disorder. This review article is presented to compose all the new information on its phytochemical and pharmacological activities. Studies indicate Hansraj(Adiantum capillus-veneris) possessesantioxidant, wound healing action, anti-microbial and anti-fungal, anti-diabetic, antipyretic activity, it is contraindicated in pregnancy due to its anti-implantation effect. Most common use of Hansraj (Adiantum capillus-veneris) in hair problem because it prevent from alopecia and dandruff. These results are very motivating and indicate this herb should be more explore to confirm these results and reveal other potential and protective effect. Clinical trials using Hansraj (Adiantum capillus-veneris) for a variety of conditions should also be conducted.
A frozen bag of genetically engineered blood or a bag of cells can change the life of persons forever; this is the new era of precision gene medicine. Many debilitating diseases can be completely cured with some financial toxicity, but in front of a lifetime suffering this financial toxicity is bearable and manageable.
Sickle cells disease (SCD), a blood disorder which damages multiple organs and excruciating pains leads to multiple morbidities. SCD occurs because of the defect in HBB gene, single mutation in this gene leads to formation of haemoglobin S, which leads to sickling, sticky and crescent-shaped red blood cells in slight hypoxic conditions. Leading to strokes, heart attacks and other critical organs damages in multiple ways in multiple times over period of time. This increases morbidity and early mortality. As this is disease is recessively heritable from parents and high degrees of penetrance in off springs. This disease thought to have originated in Africa and have protective effects against endemic malaria.
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