Physicochemical and bone regeneration studies using scaffoldings of pure natural hydroxyapatite or associated with Nb2O5

Prado, Gabriela de Castro; Weinand, W. R.; Volnistem, Eduardo Azzolini; Baesso, Mauro Luciano; Noronha, Jéssica Nayara Gimenez; Truite, Cecília Valente Rodrigues; Souza, Bruna Milhomens de; Bonadio, T. G. M.; Reis, Paulo José dos; Hernandes, Luzmarina

doi:10.1016/j.matchemphys.2021.124922

Cited by 11 publications

(2 citation statements)

References 59 publications

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“…The ideal bone repair material must possess good biocompatibility to maximize the osteogenesis process and good degradability to accelerate the regeneration of bone. These characteristics are the requirements for the implantation site of the scaffold [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Physicochemical Characterization of Thermally Processed Goose Bone Ash for Bone Regeneration

Rahman

Abdullah

Radhi

et al. 2023

JFB

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Goose bone is traditionally applied for many ailments including bone fractures. Goose bone that consists of calcium phosphate plays a major role in bone regeneration. In this study, the production of goose bone ash (GBA) was translated from a traditional process into one of a laboratory scale via thermal and mechanical methods. The GBA was thermally processed via calcination at 300 °C and 900 °C. The differences in physicochemical properties between studied GBA (SGBA) and commercial GBA (CGBA) were elucidated via Fourier transform infrared (FT-IR), X-ray fluorescence (XRF), X-ray diffraction (XRD) and electron diffraction X-Ray (EDX). The morphological properties of SGBA and CGBA were characterized using field emission scanning electron microscopy (FESEM) in which nano-sized particles were detected. The results showed that the SGBA of 300 °C had comparable physicochemical properties to those of CGBA. A high processing temperature was associated with decreasing organic compounds and increasing crystallinity. The finding from EDX suggests that sintering at 900 °C (SGBA 900) demonstrated the presence of hydroxyapatite in the mineralogical phase and had a Ca/P atomic ratio of 1.64 which is comparable to the ideal stoichiometric ratio of 1.67. Findings from this study could be used for the further exploration of GBA as a potential material for bone regeneration via the elucidation of their biological properties in the next experimental setting.

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Section: Introductionmentioning

confidence: 99%

Physicochemical Characterization of Thermally Processed Goose Bone Ash for Bone Regeneration

Rahman

Abdullah

Radhi

et al. 2023

JFB

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“…However, only 50 to 60% of the total catch is available for commercialization, while carcasses, dead or damaged fish are discarded, generating a large amount of solid waste thrown into the environment, which causes pollution and risks to public health [18]. The residues can be used for the production of calcium phosphatebased bioceramics, with excellent bioperformance for bone regeneration [19][20][21][22][23].…”

Section: Introductionmentioning

confidence: 99%

Bioperformance Studies of Biphasic Calcium Phosphate Scaffolds Extracted from Fish Bones Impregnated with Free Curcumin and Complexed with β-Cyclodextrin in Bone Regeneration

et al. 2022

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Fish bones are a natural calcium phosphate (CaP) sources used in biomaterials production for bone regeneration. CaP scaffolds can be enriched with other substances with biological activity to improve bone repair. This study aimed to evaluate the physicochemical properties and bone regeneration potential of biphasic calcium phosphate (BCP) scaffolds impregnated with free curcumin (BCP-CL) or complexed with β-cyclodextrin (BCP-CD) compared to BCP scaffolds. Rietveld’s refinement showed that BCP is composed of 57.2% of HAp and 42.8% of β-TCP and the molar ratio of Ca/P corresponds to 1.59. The scaffolds presented porosity (macro and microporosity) of 57.21%. Apatite formation occurred on the BCP, BCP-CL, and BCP-CD surface, in vitro, in SBF. Micro-Raman technique showed a reduction in the dissolution rate of β-TCP in the curcumin-impregnated scaffolds over time, and in vivo studies on critical-size defects, in rat calvaria, had no additional regenerative effect of BCP-CL and BCP-CD scaffolds, compared to BCP scaffolds. Despite this, the study showed that curcumin impregnation in BCP scaffolds prolongs the release of the β-TCP phase, the BCP- phase with the higher osteoinductive potential, representing an advantage in tissue engineering.

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Hydroxyapatite based for bone tissue engineering: innovation and new insights in 3D printing technology

et al. 2023

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Physicochemical and bone regeneration studies using scaffoldings of pure natural hydroxyapatite or associated with Nb2O5

Cited by 11 publications

References 59 publications

Physicochemical Characterization of Thermally Processed Goose Bone Ash for Bone Regeneration

Physicochemical Characterization of Thermally Processed Goose Bone Ash for Bone Regeneration

Bioperformance Studies of Biphasic Calcium Phosphate Scaffolds Extracted from Fish Bones Impregnated with Free Curcumin and Complexed with β-Cyclodextrin in Bone Regeneration

Hydroxyapatite based for bone tissue engineering: innovation and new insights in 3D printing technology

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