Physicochemical properties of functionalized carbon-based nanomaterials and their toxicity to fishes

Felix, Lindsey C.; Ede, James D.; Snell, Dana A.; Oliveira, Taiane Maria de; Martinez‐Rubi, Yadienka; Simard, Benoît; Luong, John H. T.; Goss, Greg G.

doi:10.1016/j.carbon.2016.03.041

Cited by 31 publications

(15 citation statements)

References 65 publications

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“…The reported SWCNT toxicity depends on the length, surface modifications, agglomeration state and purity. 10,28 For example, Felix et al (2016) 10 investigated the effect of the physicochemical properties of SWCNTs on their toxicity and suggested that surface functionality plays a key role in determining their toxicity. In the study, the length, surface modifications, agglomeration state and purity of SWCNTs were checked.…”

Section: Characterization Of Swcntsmentioning

confidence: 99%

“…The toxicity, bioaccumulation and fate of SWCNTs in some freshwater organisms have been studied, such as Pseudokirchneriella subcapitata, 7 Daphnia magna, 8 Lymnea luteola 9 and Danio rerio. 10 Besides, the development toxicity of SWCNTs on rare minnow embryos and larvae was also investigated in our previous work. 11 The mechanism for the toxicity of CNTs is mainly a combined effect of agglomeration, shading, physical interactions and oxidative stress.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The developmental toxicity, bioaccumulation and distribution of oxidized single walled carbon nanotubes in Artemia salina

Zhu

et al. 2018

Toxicol. Res.

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Section: Characterization Of Swcntsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The developmental toxicity, bioaccumulation and distribution of oxidized single walled carbon nanotubes in Artemia salina

Zhu

et al. 2018

Toxicol. Res.

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“…Likewise, Freixa et al (2018) concluded that carbon-based nanomaterials (i.e., C 60 , SWNTs, MWNTs, and graphene) are slightly acute toxic for most aquatic organisms (i.e., algae, crustacean, and fish) (10 mg/ L < EC 50 ≤ 100 mg/L). In contrast, existing reports of acute toxicity induced by nanocellulose materials indicate lack of effects at concentrations below 100 mg/L (Felix et al, 2016;Harper et al, 2016), not to mention that in some cases the L(E)C 50 values for organisms of different trophic levels were all higher than 1 g/L (Kovacs et al, 2010).…”

Section: Comparing Ecotoxicological Effects Induced By Nanocellulose mentioning

confidence: 73%

Oxidative stress actuated by cellulose nanocrystals and nanofibrils in aquatic organisms of different trophic levels

Wang

Song

et al. 2020

NanoImpact

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Nanocellulose is a functional material derived from natural carbon-based polymers. These nanomaterials are biodegradable and renewable in nature and hence are seen as environmentally-friendly materials in many applications. The use of such innovative materials is accelerating and inescapable there is a need to test these presumed environmentally-friendly materials with regard to their ecotoxicity. Here, the acute toxicity and the oxidative stress of nanocelluloses as induced to three aquatic organisms of different trophic levels, namely Scenedesmus obliquus, Daphnia magna, and Danio rerio, were studied in relation to the composition and morphology of the celluloses. Wood-based cellulose nanocrystals (CNCs), cotton-based CNCs, and cotton-based cellulose nanofibrils were selected as model compounds. The results clearly demonstrated a lack of impact of the different nanocellulose materials on apical endpoints like growth inhibition and mortality after short-term exposure. The nanocellulose materials did activate oxidative stress as evoked by reactive oxygen species in the three aquatic organisms. Key factors ascertained to induce the oxidative stress were the composition and morphology. The nanocellulose induced oxidative stress was observed for all the species at concentrations higher than 0.01 mg/L. This finding suggests a more general revelation of oxidative stress being a characteristic mechanism for nanocellulose toxicity to aquatic organisms.

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“…Treatment with pristine SWCNTs and the amide variant of functionalized SWCNTs (1.0, 100, 250, and 500 μg•mL −1 ) for 48 h was shown to have no significant difference in terms of lethal effects for C. elegans as compared with a control group [43]. In other in-vivo models, treatment with SWCNTs−COOH at concentrations of 1.0, 10, 50, 100, or 200 mg•L −1 for 72 h significantly reduced the survival of zebrafish (Danio rerio) embryos [47]. SWCNTs−COOH concentrations of 0.25, 0.5 and 0.75 mg kg −1 body weight induced hepatotoxicity in mice through activation of the oxidative stress mechanism [48].…”

Section: Characterization Of Swcnts−coohmentioning

confidence: 95%

The Impact of Background-Level Carboxylated Single-Walled Carbon Nanotubes (SWCNTs−COOH) on Induced Toxicity in Caenorhabditis elegans and Human Cells

Hou

Tsai

et al. 2022

IJERPH

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Single-walled carbon nanotubes (SWCNTs) are widely utilized for industrial, biomedical, and environmental purposes. The toxicity of Carboxylated SWCNTs (SWCNTs−COOH) in in vivo models, particularly Caenorhabditis elegans (C. elegans), and in vitro human cells is still unclear. In this study, C. elegans was used to study the effects of SWCNTs−COOH on lethality, lifespan, growth, reproduction, locomotion, reactive oxygen species (ROS) generation, and the antioxidant system. Our data show that exposure to ≥1 μg·L−1 SWCNTs−COOH could induce toxicity in nematodes that affects lifespan, growth, reproduction, and locomotion behavior. Moreover, the exposure of nematodes to SWCNTs−COOH induced ROS generation and the alteration of antioxidant gene expression. SWCNTs−COOH induced nanotoxic effects at low dose of 0.100 or 1.00 μg·L−1, particularly for the expression of antioxidants (SOD-3, CTL-2 and CYP-35A2). Similar nanotoxic effects were found in human cells. A low dose of SWCNTs−COOH induced ROS generation and increased the expression of catalase, MnSOD, CuZnSOD, and SOD-2 mRNA but decreased the expression of GPX-2 and GPX-3 mRNA in human monocytes. These findings reveal that background-level SWCNTs−COOH exerts obvious adverse effects, and C. elegans is a sensitive in vivo model that can be used for the biological evaluation of the toxicity of nanomaterials.

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Physicochemical properties of functionalized carbon-based nanomaterials and their toxicity to fishes

Cited by 31 publications

References 65 publications

The developmental toxicity, bioaccumulation and distribution of oxidized single walled carbon nanotubes in Artemia salina

The developmental toxicity, bioaccumulation and distribution of oxidized single walled carbon nanotubes in Artemia salina

Oxidative stress actuated by cellulose nanocrystals and nanofibrils in aquatic organisms of different trophic levels

The Impact of Background-Level Carboxylated Single-Walled Carbon Nanotubes (SWCNTs−COOH) on Induced Toxicity in Caenorhabditis elegans and Human Cells

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