Physicochemical study of floranol, its copper(II) and iron(III) complexes, and their inhibitory effect on LDL oxidation

The characterisation of structural and antioxidant properties of isoflavone metal chelates

“…The promotion of antioxidant activity of flavonoids using copper has been reported in numerous publications but to the authors' knowledge, this is the first reporting of antioxidant activity of Cu(II) isoflavone chelates. [10,23,36].…”

“…The knowledge of how isoflavones interact with metals is of interest as Cu(II) and Fe(III) are common metal species present in the human body and knowledge of these interactions can give information as whether these metal interactions will lead to health benefits such as phytosoya supplements [6,7]. This could be useful for using isoflavones as natural chelating agents [8] such as iron induced lipid peroxidation [9] in the human body.…”

Synthesis, structure, DNA-binding properties, and antioxidant activity of copper(II) and cobalt(II) complexes with bis(N-allylbenzimidazol-2-ylmethyl)benzylamine

“…In this study, the synthesis, characterization, and DNA-binding activities of two transition metal complexes with bis(Nallylbenzimidazol-2-ylmethyl)benzylamine are presented. According to relevant reports in the literature [15][16][17][18], similar transition metal complexes can exhibit antioxidant activity. We therefore also conducted an investigation into the hydroxyl radical scavenging properties of these complexes.…”

Synthesis, characterization, spectroscopic and antioxidation studies of Cu(II)–morin complex

“…In particular, it is widely known that flavonoids can react with harmful free radicals such as hydroxyl or peroxyl, thus preventing the oxidation of lipids and other important molecular agents. Furthermore, transition metal ions (especially copper) in their reduced oxidation state can promote the formation of free radicals [9,10]. Redox reactions are also observed through the change of the oxidation state of the metal, jointly with the oxidation of the flavonoids by loss of hydrogen.…”