Seldin and Giebisch's the Kidney 2013
DOI: 10.1016/b978-0-12-381462-3.00074-4
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Physiologic Principles in the Clinical Evaluation of Electrolyte, Water, and Acid–Base Disorders

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Cited by 5 publications
(4 citation statements)
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“…In metabolic acidosis secondary to diarrhea, ammonium excretion is enhanced, thereby adding "unmeasured cations" and inducing a more negative UAG (14). With renal tubular acidosis and the metabolic acidosis of CKD, robust increases in ammonium excretion do not occur, resulting in a more positive UAG (14,15). However, the ability of the UAG to predict urine ammonium concentration and assess clinical risk in patients with CKD is questionable.…”
Section: Introductionmentioning
confidence: 99%
“…In metabolic acidosis secondary to diarrhea, ammonium excretion is enhanced, thereby adding "unmeasured cations" and inducing a more negative UAG (14). With renal tubular acidosis and the metabolic acidosis of CKD, robust increases in ammonium excretion do not occur, resulting in a more positive UAG (14,15). However, the ability of the UAG to predict urine ammonium concentration and assess clinical risk in patients with CKD is questionable.…”
Section: Introductionmentioning
confidence: 99%
“…As renal failure progresses, the decrease in uCr causes FE Na to increase even without a change in urinary sodium, hence complicating the interpretation of the index. (43,44) There are also marked differences in uCER in patients who have undergone kidney transplantation, with extrapolated uCER ranging from under 300 mg/day in a patient with delayed graft function to more than 2,100 mg/day in a patient with prompt graft function. (37) This could be significant since several studies involving potential biomarkers for predicting graft loss or delayed graft function, such as NGAL, IL-18, and KIM-1, often normalise biomarker excretion rates to uCr.…”
Section: Disease States and Acuitymentioning
confidence: 99%
“…Seu prognóstico é semelhante à sua representação clínica, pois alguns pacientes conseguem se manter com um tratamento mínimo, e outros evoluem à insuficiência renal em estágio terminal. Nestes casos, as crianças são as mais afetadas, tendo seu desenvolvimento físico e, possivelmente, psicológico prejudicados porque geralmente desenvolvem a doença por causas primárias, desse modo, sofrem com as ATRs durante a fase de crescimento 15 . Crianças com ATR podem apresentar baixo crescimento, depleção de volume, fadiga ou letargia 16 .…”
Section: Resultsunclassified