Physiological benefits likely underlie the systematic recruitment of thermoeffectors

Vargas, Nicole T.; Schlader, Zachary J.

doi:10.1080/23328940.2017.1415094

Cited by 5 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The exposure to heat stress could have an impact on the toxicokinetics of inhaled chemicals by changing some values of cardiopulmonary parameters, as well as organ blood flows (Marchand and Haddad 2017). Compared to gradual physical exertion where the muscle blood flow increase (Guyton 1991;Raff and Levitzky 2011;Rhoades and Bell 2013), heat stress increases the skin blood flow (Schlader et al, 2016(Schlader et al, , 2018aRavanelli et al 2017;Vargas and Schlader, 2018), in both cases, at the expense of blood flows of other organs. The decrease of the arterial pressure enhances an increase of the Q value (Rowell et al 1969;Minson et al 1998;Yamazaki et al 2000;Stöhr et al 2011;Wilson and Crandall 2011;Ogoh et al 2013;Pranskunas et al 2015) and the redistribution of organ blood flows (Rowell et al 1970;Crandall et al 2008;Crandall and González-Alonso 2010).…”

Section: R a F Tmentioning

confidence: 99%

Cardiopulmonary values and organ blood flows before and during heat stress: data in nine subjects at rest in the upright position

Brochu

Ménard

Marchand

et al. 2021

Can. J. Physiol. Pharmacol.

View full text Add to dashboard Cite

Physiological changes associated with thermoregulation can influence the kinetics of chemicals in the human body, such as alveolar ventilation (VA) and redistribution of blood flow to organs. In this study, the influence of heat stress on various physiological parameters was evaluated in nine male volunteers during sessions of exposure to wet blub globe temperatures (WBGT) of 21, 25 and 30°C for four hours. Skin and core temperatures and more than twenty cardiopulmonary parameters were measured. Liver, kidneys, brain, skin and muscles blood flows were also determined based on published measurements. Results show that most subjects (8 out of 9) have been affected by the inhalation of hot and dry air at the WBGT of 30°C. High respiratory rates, superficial tidal volumes and low VA values were notably observed. The skin blood flow has increased by 2.16-fold, whereas the renal blood flow and liver blood flow have decreased by about by 11 and 18% respectively. A complete set of key cardiopulmonary parameters in healthy male adults before and during heat stress was generated for use in PBPK modeling. A toxicokinetic studies are ongoing to evaluate the impact of heat stress on the absorption, biotransformation and excretion rates of volatile xenobiotics.

show abstract

Section: R a F Tmentioning

confidence: 99%

Cardiopulmonary values and organ blood flows before and during heat stress: data in nine subjects at rest in the upright position

Brochu

Ménard

Marchand

et al. 2021

Can. J. Physiol. Pharmacol.

View full text Add to dashboard Cite

show abstract

“…Figure 2: Hierarchy of activation of physiological autonomous(vasomotor, shivering, sweating) and behavioural body responses (simplified fromVargas and Schlader 2018, based on Schlader et al 2017). This figure is a reprint from:Hellwig, R. T.et al (2020c) and was published first In S. Roaf, F.Nicol, & W. Finlayson (Eds.…”

mentioning

confidence: 99%

Guidelines for low energy building design based on the adaptive thermal comfort concept - Technical report: IEA EBC Annex 69: Strategy and Practice of Adaptive Thermal Comfort in Low Energy Buildings.

Hellwig¹,

Teli²,

Schweiker³

et al. 2022

View full text Add to dashboard Cite

The adaptive thermal comfort concept has been developed over many years and proven in numerous field studies (e.g. Webb 1964, Nicol and Humphreys 1973, Auliciems 1981b, de Dear et al. 1997, McCartney and Nicol 2002, Manu et al. 2016), showing that people are satisfied with a wide range of thermal conditions. Prerequisite is that people are provided with means to make themselves comfortable, that they know which opportunities they have, that it is socially acceptable to use these opportunities and that they are willing to use them (Hellwig, 2015). However, the overall understanding of how to design for such opportunities enabling the occupant to make themselves comfortable in relation to climate and building type, thus how to convert the adaptive thermal comfort concept into building design and concepts for operating buildings, is still limited. There are still common misunderstandings in the interpretation of the adaptive comfort approach among building planners and operators e.g. regarding the amount of control, the seriousness of this topic or the level of information needed by occupants for which reason guidance (e.g. CIBSE 2010, Cook et al. 2020) and knowledge transfer (e.g. Hellwig and Boerstra 2017, 2018) is absolutely essential. Consequently, there is still a gap between scientific research and real-world-application, which this report aims to diminish.

show abstract

Influences of ovarian hormones on physiological responses to cold in women

2021

View full text Add to dashboard Cite

Physiological benefits likely underlie the systematic recruitment of thermoeffectors

Cited by 5 publications

References 5 publications

Cardiopulmonary values and organ blood flows before and during heat stress: data in nine subjects at rest in the upright position

Cardiopulmonary values and organ blood flows before and during heat stress: data in nine subjects at rest in the upright position

Guidelines for low energy building design based on the adaptive thermal comfort concept - Technical report: IEA EBC Annex 69: Strategy and Practice of Adaptive Thermal Comfort in Low Energy Buildings.

Influences of ovarian hormones on physiological responses to cold in women

Contact Info

Product

Resources

About