Physiological Changes in Intermediary Metabolism of Various Species of Ruminants Incident to Functional Development of Rumen

McCandless, Esther L.; Dye, J. A.

doi:10.1152/ajplegacy.1950.162.2.434

Cited by 65 publications

(18 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Tlie results of the glucose tolerance tests agree with those reported by McCandless and Dye (1950) and show that as the yonng lamb becomes older and develops the feeding habits characteristic of the adult, the return to the preinjection level following the administration of glucose is much more prolonged.…”

Section: Houhs Aftsrsupporting

confidence: 86%

“…The observations presented here, aud those of McCandless and Dye (1950) suggest that some aspects of tho carbohydrate metabolism of the yonng lamb differ from those of the adult and more closely resemble those of the non-rnminant.…”

Section: Houhs Aftsrsupporting

confidence: 60%

“…Tlie adult rnminant, however, has not the same capacity to deal with injected glucose and so the subsequent hyper-glyeaemia is sustained for a longer periotl (McCandless and Dye, 1950). The report of very high concentrations of sugar in the blood of foetal lambs (Passmore and Schlossaiann, 1938), the observation by Cole and IlitchcoeU (1946) that eoasiderable quantities of fruetose are present in the blood of foetal sheep, and the confirmation of this by Bacon and Boll (1948) have raised further interesting problems associated with the metabolism of sugar in tlie very young animal.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Carbohydrate Metabolism in the Young Lamb

Jarrett

1952

Aust J Exp Biol Med

View full text Add to dashboard Cite

The rurainant derive.s its main souree of energy from simple fatty aeids produced by fermentation in its paunch. This implie.s an intermediary metabolism of which the low concentration of sugar in the blootl of the adnlt ruminant is po&sibly a reflection. The metabolism of the newly born ruminant, however, might be expeetcd to simulate elosely that of other animals as, during the period before rumination begins, the lamb derives a considerable part of its energy from lactose.The blootl of the yonng lamb and calf ha.s been reported to contain relatively high concentrations of sngar (Jarrett and Potter, 1948; McCandless and Dye, li)49) and tbe tolerance of young ruminants to glucose administered by intraveuouK injeetion is typical of non-ruminants. Tlie adult rnminant, however, has not the same capacity to deal with injected glucose and so the subsequent hyper-glyeaemia is sustained for a longer periotl (McCandless and Dye, 1950). The report of very high concentrations of sugar in the blood of foetal lambs (Passmore and Schlossaiann, 1938), the observation by Cole and IlitchcoeU (1946) that eoasiderable quantities of fruetose are present in the blood of foetal sheep, and the confirmation of this by Bacon and Boll (1948) have raised further interesting problems associated with the metabolism of sugar in tlie very young animal.Following a few preliminary obsen^ations during the 1947 lambing season (Jarrett ajid Potter, 1948) a further investigation was made of tlic concentrations of reducing sugars, fruetose, pyruvic acid and total volatile acids in the blood of yoimg lambs, and of glucose tolerance at birth and during the first few weeks of life. EXPERIMENTAL METHODS.Blood samples were taken from the jugular vein of newly-born Merino laniita as soon as possilik' after birth and at intervals thereafter for a period of 10-:2 weeks. Tn most cases the initial B.imple was obtained a few minutes after delivery. Some animals were allowed to suek immediately; others were not aUowed access to the ewe for 8-15 hours. During the first day blood samples were taken at 1, 2, 4, 8, 12 and IS hours, subsequently mico a day for seven days, and thereafter at weekly intervals. Tlie tolerance of the lamb to injected glucose waa determined at weekly intervals. Glucose equivalent to 1 gm./kg. was injected aa a 25 p.c.

show abstract

Section: Houhs Aftsrsupporting

confidence: 86%

Section: Houhs Aftsrsupporting

confidence: 60%

mentioning

confidence: 99%

See 1 more Smart Citation

Carbohydrate Metabolism in the Young Lamb

Jarrett

1952

Aust J Exp Biol Med

View full text Add to dashboard Cite

show abstract

“…One consequence of the low availability of free glucose is that adult pecorans have extremely low blood sugar levels, about half that of other adult mammals (Moir, 1968). Adult pecorans also have a low glucose tolerance and show poor resistance of the blood sugar levels to fasting (McCandless and Dye, 1950). Whether this factor represents a real disadvantage of forestomach fermentation is not clear.…”

Section: And 3)mentioning

confidence: 99%

The Evolutionary Strategy of the Equidae and the Origins of Rumen and Cecal Digestion

1976

View full text Add to dashboard Cite

“…t [1][2][3][4][5][6][7] a u ts and young lam s or non-rumman s. However, the contribution of glucose recycling via Cori cycle to the glucose synthesis has not been examined in relation to the developmental changes in the carbohydrate metabolism in ruminants. Such changes might reflect on the rate of glucose recycling via Cori cycle which is accomplished through the gluconeogenic pathway.…”

mentioning

confidence: 99%