Physiological impact of high-flow nasal cannula therapy on postextubation acute respiratory failure after pediatric cardiac surgery: a prospective observational study

Shioji, Naohiro; Iwasaki, Tadaaki; Kanazawa, Tomoyuki; Shimizu, Kazuyoshi; Suemori, Tomohiko; Sugimoto, Katsuyoshi; Kuroe, Yasutoshi; Morimatsu, Hiroshi

doi:10.1186/s40560-017-0226-z

Cited by 24 publications

(25 citation statements)

References 19 publications

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“…After searching for duplicates, screening titles, and abstracts, we reviewed 14 records in full text, in which 10 studies were excluded. Two of these articles were published in children, [ 22 , 23 ] 2 were no relevant control group, [ 24 , 25 ] 1 lung transplant was not included our outcomes, [ 26 ] and 3 of the literature did not report the main outcome [ 27 – 29 ] and 2 trials were controlled studies of HFNC after abdominal surgery, [ 30 , 31 ] eventually 4 trials were enrolled in our final analysis. [ 32 – 35 ] The process for literature search and study selection is presented in Figure 1 .…”

Section: Resultsmentioning

confidence: 99%

Effect of high-flow nasal cannula oxygen therapy vs conventional oxygen therapy on adult postcardiothoracic operation

Cao²,

Zhang³

et al. 2018

Medicine

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Introduction:The effect of high-flow nasal cannula (HFNC) on adult post cardiothoracic operation remains controversial. We conducted a meta-analysis of randomized controlled trials to evaluate the effect of HFNC and conventional oxygen therapy (COT) on postcardiothoracic surgery.Methods:A search was conducted in Embase, MEDLINE, Ovid, and Cochrane databases until December, 2017 for all the controlled study to compare HFNC with COT in adult postcardiothoracic surgery. Two authors extracted data and assessed the quality of each study independently. The meta-analysis was performed by using RevMan 5.3. The primary outcome was the rate of escalation of respiratory support rate and pulmonary complications; secondary outcome included the length of intensive care unit (ICU) stay and length of hospital stay and the rate of intubation.Results:Four studies that involved 649 patients were included in the analysis. No significant heterogeneity was found in outcome measures. Compared with COT, HFNC were associated with a significant reduction in the escalation of respiratory support (odds ratio [OR] = 0.44, 95% confidence interval [CI] = 0.29−0.66, P < .001) and pulmonary complications (OR = 0.28, 95% CI = 0.13−0.6, P = .001). There were no significant differences in the reintubation rate (OR = 0.33, 95% CI = 0.02−5.39, P = .43), length of ICU stay (weighted mean difference = 0.11; 95% CI = −0.44 −0.26, P = .14) or length of hospital stay (weighted mean difference = −0.15, 95% CI = −0.46 −0.17, P = .36) between the 2 groups. No severe complications were reported in either group.Conclusion:The HFNC could reduce respiratory support and pulmonary complications, and it could be safely administered for adult postcardiothoracic surgery. Further large-scale, randomized, and controlled trials are needed to update this finding.

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Section: Resultsmentioning

confidence: 99%

Effect of high-flow nasal cannula oxygen therapy vs conventional oxygen therapy on adult postcardiothoracic operation

Cao²,

Zhang³

et al. 2018

Medicine

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“…HFNC therapy improved the respiration rate of pediatric patients with postextubation acute respiratory failure after cardiac surgery. 27) HFNC showed a lower failure rate after extubation compared with that of the conventional oxygen therapy group in the ICU. 28) Studies comparing the efficacy and safety of NRSs are rare.…”

Section: Other Indicationsmentioning

confidence: 76%

High-flow nasal cannula oxygen therapy in children: a clinical review

Kwon

2020

Clin Exp Pediatr

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High-flow nasal cannula (HFNC) is a relatively safe and effective noninvasive ventilation method that was recently accepted as a treatment option for acute respiratory support before endotracheal intubation or invasive ventilation. The action mecha nism of HFNC includes a decrease in nasopharyngeal resistance, washout of dead space, reduction in inflow of ambient air, and an increase in airway pressure. In preterm infants, HFNC can be used to prevent reintubation and initial noninvasive respiratory support after birth. In children, flow level adjustments are crucial considering their maximal efficacy and complications. Randomized controlled studies suggest that HFNC can be used in cases of moderate to severe bronchiolitis upon initial low-flow oxygen failure. HFNC can also reduce intubation and mechanical ventilation in children with respiratory failure. Several observational studies have shown that HFNC can be beneficial in acute asthma and other respiratory distress. Multicenter randomized studies are warranted to determine the feasibility and adherence of HFNC and continuous positive airway pressure in pediatric intensive care units. The development of clinical guidelines for HFNC, including flow settings, indications, and contraindications, device management, efficacy identification, and safety issues are needed, particularly in children.

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“…Çalışmalar yüksek akımlı nazal kanül oksijenizasyon kullanımının hem genel çocuk servisi ve acil servislerde hem de yoğun bakım ünitelerinde güvenli olduğu sonucuna varmıştır (17,(19)(20)(21). Bununla beraber, yapılan çalışmalarda YANKO tedavisi verilen hastalarda hayatı tehtid edecek kadar ciddi pnömotoraks geliştiği de bildirmiştir (17,22,23 (30). Çalışmamızda hastaların çocuk yoğun bakım ünitesine yatış laktat düzeyi ile 6, 12 ve 24. saat laktat düzeyleri karşılaştırıldığında, yatış ve 24. saat laktat değerleri arasında istatistiksel olarak anlamlı fark saptandı.…”

Section: Introductionunclassified

Evaluation of Patients Receiving High-flow Nasal Cannula Oxygenation Therapy in a Pediatric Intensive Care Unit

Vural¹,

Tolunay²,

Tolunay³

2022

tybd

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Objective: Patients hospitalized in pediatric intensive care units require various rates of respiratory and oxygen support therapies. Invasive and non-invasive treatment methods are used as respiratory support treatment, and new technologies are being used in oxygen delivery systems. This study aimed to investigate the success and complication rates of high flow nasal cannula oxygen (HFNCO) therapy in the pediatric intensive care unit. Materials and Methods: In this study, demographic characteristics, treatment processes and success/complication rates of the patients treated with HFNCO between 01.02.2018 and 01.02.2019 in the pediatric intensive care unit of Pediatric Clinic of Adana City Training and Research Hospital were evaluated retrospectively. Results: The mean age of 131 patients included in the study was 41.82 ± 46.88 months. The indications for hospitalization of the patients to pediatric intensive care unit or the reasons for starting HFNCO treatment were as follows: pneumonia in 59.5%, asthma/bronchiolitis in 14.5%, sepsis in 6.9%, post-extubation stridor / respiratory distress in 16.8% and other causes in 2.3%. HFNCO treatment was evaluated as successful in 90.8% of the patients and unsuccessful in 9%. Complications were seen in five patients (3.8%), pneumothorax in four patients, and abdominal distension in one patient. Conclusion: Studies on HFNCO therapy in terms of therapeutic efficacy, safety, and indications for use are not yet sufficient in quantity and terms of scientific evidence. To evaluate the efficacy and complications of HFNCO treatment, multicenter randomized controlled trials are needed in different patient groups.

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Physiological impact of high-flow nasal cannula therapy on postextubation acute respiratory failure after pediatric cardiac surgery: a prospective observational study

Cited by 24 publications

References 19 publications

Effect of high-flow nasal cannula oxygen therapy vs conventional oxygen therapy on adult postcardiothoracic operation

Effect of high-flow nasal cannula oxygen therapy vs conventional oxygen therapy on adult postcardiothoracic operation

High-flow nasal cannula oxygen therapy in children: a clinical review

Evaluation of Patients Receiving High-flow Nasal Cannula Oxygenation Therapy in a Pediatric Intensive Care Unit

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