2023
DOI: 10.1177/09544062231181805
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Physiological loading-induced streaming potentials in osteogenesis imperfecta bone

Abstract: Mechanical loading on bone generates streaming potentials (SPs) and streaming currents (SCs) in lacunar-canalicular fluid which act as stimuli to bone cells namely osteocytes. It is observed that both lacunar and vascular porosity significantly affect streaming potentials and thus the bone remodelling activities. Increased porosity levels associated with bone disorders such as especially osteogenesis imperfecta (OI) and osteoporosis considerably reduce SPs which may further negatively affect bone’s mechanoregu… Show more

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Cited by 2 publications
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