Physiology of Neuxstrophil Proliferation, Maturation and Circulation

Dr, Boogs

doi:10.1016/s0308-2261(21)00094-1

Cited by 13 publications

References 58 publications

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Chronic myelogenous leukemia

Moloney¹

1978

Cancer

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Chronic myelogenous leukemia (CML) is a relatively rare disease, with a number of features that make it especially suitable for observations on leukemogenesis in man. These include known etiologic agents, often a prolonged preclinical and active stage, cells with identifiable morphological and histochemical characteristics and the presence of the unique Ph' chromosome. The transition of CML to blast crisis is a catastrophic event; however, recent clinical and biochemical studies have raised important questions as to the nature and origin of blast cells in this disease. During the past 10 years, we have followed 113 cases olf CML throughout their course and results of observations on the clinical, hematological and other apsects of the disease are presented in this communication.

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Chronic myelogenous leukemia

Moloney¹

1978

Cancer

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The hemodialysis‐induced reaction in patients with leukemia

Berman¹

1977

Med. Pediatr. Oncol.

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The white blood cell count response was documented in various patients following transfusions of 500 ml of autologous or unrelated donor blood that had been subjected to 10 minutes of dialysis with 15 minutes of stagnation. Patients studied included 1 patient with acute nonlymphocytic (ANLL) and 2 patients with chronic lymphocytic leukemia (CLL). The control group consisted of 4 patients with renal failure. The ANLL patient showed a normal two-phase reaction after administration of donor's blood. It is possible that even under conditions of severe disturbance of hemopoiesis the general dependence on normal humoral regulation remains. The CLL patients showed a marked drop in circulating WBC in the first descending phase of the hemodialysis-induced reaction (HDIR). All blood cell types including lymphocytes and blast cells took part in this decrease of blood count; this suggests a cell-nonspecific effect. It is presumed that leukocytes that leave the circulation do not return into the blood and the procedure may be considered as a form of leukophoresis in vivo, with possible therapeutic value.

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Bone Marrow Macrophages

Hudson¹,

Shortland²

1980

Morphology

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Physiology of Neuxstrophil Proliferation, Maturation and Circulation

Cited by 13 publications

References 58 publications

Chronic myelogenous leukemia

Chronic myelogenous leukemia

The hemodialysis‐induced reaction in patients with leukemia

Bone Marrow Macrophages

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