2022
DOI: 10.1007/s13399-022-02436-x
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Phyto-mediated synthesis of CuO nanoparticles using aqueous leaf extract of Artemisia deserti and their anticancer effects on A2780-CP cisplatin-resistant ovarian cancer cells

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Cited by 20 publications
(7 citation statements)
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“…The cytotoxicity of CuONPs was assessed on three cell lines, and findings revealed dose- and cell type-dependent effects, as higher toxicity was detected in LoVo cells when compared to MKN-45 cells and normal fibroblasts. In consistent with our results, it has been reported that CuONPs induced apoptosis in ovarian cancer cells while causing negligible toxicity on human normal skin fibroblasts [ 20 ]. Similarly, biosynthesized CuONPs had good cytotoxicity against human breast and lung carcinoma cells with a minimum toxic effect on normal mouse fibroblasts [ 21 ].…”
Section: Discussionsupporting
confidence: 93%
“…The cytotoxicity of CuONPs was assessed on three cell lines, and findings revealed dose- and cell type-dependent effects, as higher toxicity was detected in LoVo cells when compared to MKN-45 cells and normal fibroblasts. In consistent with our results, it has been reported that CuONPs induced apoptosis in ovarian cancer cells while causing negligible toxicity on human normal skin fibroblasts [ 20 ]. Similarly, biosynthesized CuONPs had good cytotoxicity against human breast and lung carcinoma cells with a minimum toxic effect on normal mouse fibroblasts [ 21 ].…”
Section: Discussionsupporting
confidence: 93%
“…Similarly, DLS analysis showed a hydrodynamic diameter at 128.57 nm, an FTIR spectrum noted at 727 and 528 cm −1 , and photoluminescence spectrum blue emissions observed at 417, 437, and 481, 509, 524 nm (green) peaks for ionized oxygen. All these results support the typical characteristic peaks of CuO/TiO 2 ‐chitosan‐farnesol nanocomposites synthesized in our study [40, 41].…”
Section: Discussionsupporting
confidence: 91%
“…Likewise, analysis of colon adenocarcinoma (CT-26) cells revealed a significant increase in the number of G2 phase cells following treatment with free Cr relative to the control (blank) cells. 79 Moreover, CuO NPs ability to arrest the cell cycle at G2 phase and prevent G2-M transition were previously reported in human lung cancer (A-549) 80 and skin cancer (A-375) 81 cells.…”
Section: Resultsmentioning
confidence: 74%