Phytobiological-facilitated Production of Silver Nanoparticles From Selected Non-cultivated Vegetables in Nigeria and Their Biological Potential

Bello, Oluwasesan M.; Oguntoye, O.S.; Dada, Adewumi O.; Bello, Oluwatoyin E.; Ali, Tijjani; Alhaji, Ahmad Abdullahi; Adeniyi, O. D.

doi:10.4274/tjps.galenos.2019.10846

Cited by 6 publications

(5 citation statements)

References 25 publications

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“…The significant decrease in MDA observed in the group treated with phytobiological formulation, compared to the ulcer group indicates that this nutrient formulation yields an improved outcome in ameliorating the adverse effects of gastric ulcer, induced via increased lipid peroxidation [30][31][32] . The result of the present study also agrees with those of previous studies reporting that supplementation with individual formulations combined in our novel nutrient formulation is found to be effective in scavenging free radicals [1,5,7,10,15,17,18,20,33] .…”

Section: Effectsupporting

confidence: 92%

“…In developing countries, herbalists and traditional healers have been reported to use phytogenic candidates for gastric ulcers treatment. Also, the application of assorted phytobiological therapies have proven to yield improved outcomes with less side effects and lower drug resistance [5] . Consequently, in recent years several anti-ulcer research studies have been centered on the development of novel phytobiological formulations to serve as substitutes for conventional chemotherapeutic agents.…”

mentioning

confidence: 99%

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Protective and Therapeutic Potential of a Novel Phytobiological Formulation of Nutrients in the Treatment of Indomethacin-Induced Gastric Ulcer

Alamri,

Harakeh,

Saber

et al. 2023

IJPS

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Therapeutic Potential of Phytobiological Formulation in the Treatment of Indomethacin-Induced Gastric UlcerGastric ulcers have been considered as a major problem worldwide. This study investigated the protective synergistic effect of a novel nutrient formulation for the protection and treatment of indomethacin-induced gastric ulcer in rat model. 24, 8 w old male rats with a body weight between 220 and 240 g, were divided into four groups and used for this study. Group 1 consists of healthy controls and group 2 consists of ulcerative animals, group 3 consists of ulcerative+phytobiological formulation treatment (80 mg/kg) and group 4 consists of omeprazole (40 mg/kg). Pre-treatment with 80 mg/kg of phytobiological formulation improved the activities of the measured antioxidant enzymes, decreased lipid peroxidation and inflammation, as evidenced by improved surface and glandular epithelium (white arrows) of phytobiological treated group stained with hematoxylin and eosin and tumor necrosis factor alpha immuno-expression when compared with the ulcer group. In conclusion, the mechanism by which this phytobiological formulation prevents indomethacininduced gastric ulcer may be mediated via improving the homeostasis of enzymatic (superoxide dismutase) and nonenzymatic (glutathione) antioxidants, inhibiting (malondialdehyde) and decreasing the formation of inflammatory cytokines (tumor necrosis factor alpha, C-reactive protein content and interleukin-10). Consequently, this phytobiological formulation may be a beneficial nutrient formulation therapy for patients diagnosed with gastric ulceration.

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Section: Effectsupporting

confidence: 92%

mentioning

confidence: 99%

Protective and Therapeutic Potential of a Novel Phytobiological Formulation of Nutrients in the Treatment of Indomethacin-Induced Gastric Ulcer

Alamri,

Harakeh,

Saber

et al. 2023

IJPS

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show abstract

“…Suitable concentrations of ion source for Ag-NPs synthesis was confrmed with golden color solution after complete reduction reaction. Te golden color indicated the maximum Ag-NPs yield when 0.01 M AgNO 3 was employed [91,92,109]. Whereas, squirrel and cider orange color with minimum Ag-NPs was yielded when 0.1 M and 0.00 1 M AgNO 3 solution was utilized.…”

Section: Discussionmentioning

confidence: 99%

Facile Synthesis and Application of Ag-NPs for Controlling Antibiotic-ResistantPseudomonas spp. and Bacillus spp. in a Poultry Farm Environment

Rahman

Rasid

Ali

et al. 2023

Journal of Nanotechnology

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This study synthesized silver nanoparticles (Ag-NPs) using silver nitrate (AgNO3) as the ion source and sodium tripolyphosphate (STPP) as reducing as well as capping agents. The synthesized Ag-NPs were confirmed initially using Ag-NPs specific λmax at 410 nm with UV-Vis spectrophotometry and homogenously distributed, 100–300 nm size, and round-shaped particles were realized through atomic force microscopy (AFM) and transmission electron microscopy (TEM) image analysis. The various reaction condition-based studies revealed 0.01 M AgNO3 yields maximum particle after 4 h reduction with 1% STPP. Bacillus spp. (n = 23/90) and Pseudomonas spp. (n = 26/90) were isolated from three different poultry farms for evaluating the antibacterial activity of Ag-NPs. Among the PCR confirmed isolates, 52% (12/23) Bacillus spp. were resistant to ten antibiotics and 65% (17/26) Pseudomonas spp. were resistant to eleven antibiotics. The representative resistant isolates were subjected to antibacterial evaluation of synthesized Ag-NPs following the well diffusion method, revealing the maximum sensitive zone of inhibition 19 ± 0.2 mm against Bacillus spp. and 17 ± 0.38 mm against Pseudomonas spp. The minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) of Ag-NPs were 2.1 μg/ml and 8.4 μg/ml, respectively, for broad-spectrum application. Finally, the biocompatibility was determined by observing the viability of Ag-NP-treated BHK-21 cell through trypan blue-based exclusion assay revealing nonsignificant decreased of cell viability ≤2MIC doses. Thus, the synthesized Ag-NPs were proven as biocompatible and sensitive to both Gram-positive and Gram-negative bacteria of the poultry farm environmental samples.

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“…These complex biomolecules assist in the reduction of metal ions and also provide stability to nanoparticles [ 13 ]. The green method of nanoparticle synthesis has been reported in different plants, including Tithonia diversifolia [ 25 ], Acalypha wilkesiana [ 26 ], Holarrhena pubescens [ 27 ] from the fern Gleichenia pectinata [ 28 ], and from different vegetable species [ 29 ].…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis of Silver Nanoparticles from Camellia sinensis and Its Antimicrobial and Antibiofilm Effect against Clinical Isolates

Ali

Jalal²,

Ahmad³

et al. 2022

Materials

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The green synthesis method of was used for the synthesis of silver nanoparticles using Camellia sinensis (green tea). The Camellia sinensis silver nanoparticles (CS-AgNPs) were characterized using different techniques, including UV-Vis (ultra violet-visible), SEM (scanning electron microscopy), TEM (transmission electron microscopy), and XRD (X-ray diffraction). The average size of the CS-AgNPs was 52 nm, according to TEM. The CS-AgNPs showed excellent antibacterial and antifungal activity. The MIC (minimum inhibitory concentration) against bacterial isolates varied from 31.25 to 62.5 µg/mL, whereas for fungal isolates, the MIC varied from 125 to 250 µg/mL. The presence of a zone in the well diffusion assay showed the antimicrobial nature of CS-AgNPs. Further, CLSM (confocal laser scanning microscopy) showed that CS-AgNPs possess antibiofilm activity. The interaction of CS-AgNPs with the Candidal cells was analyzed using TEM, and it was revealed that CS-AgNPs entered the cell and disrupted the cell machinery.

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Phytobiological-facilitated Production of Silver Nanoparticles From Selected Non-cultivated Vegetables in Nigeria and Their Biological Potential

Cited by 6 publications

References 25 publications

Protective and Therapeutic Potential of a Novel Phytobiological Formulation of Nutrients in the Treatment of Indomethacin-Induced Gastric Ulcer

Protective and Therapeutic Potential of a Novel Phytobiological Formulation of Nutrients in the Treatment of Indomethacin-Induced Gastric Ulcer

Facile Synthesis and Application of Ag-NPs for Controlling Antibiotic-ResistantPseudomonas spp. and Bacillus spp. in a Poultry Farm Environment

Green Synthesis of Silver Nanoparticles from Camellia sinensis and Its Antimicrobial and Antibiofilm Effect against Clinical Isolates

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