Phytochemical Analysis and Antioxidant Activity of Methanolic Extract of Leaves of Corchorus Olitorius

Sadat, Abdul; Hore, Mayukh; Chakraborty, Kaushik; Roy, Swarnendu

doi:10.22159/ijcpr.2017v9i5.22138

Cited by 19 publications

(15 citation statements)

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“…The traditional medicinal use of the plant in Egypt and India dates back to some 2500 years, where it was used to treat fever, diarrhea and vomiting (Islam, 2012). The antioxidant and analgesic activities of the plant leaves have been reported by Sadat, et al, (2017) and Ipav et al (2018). In Nigeria, bush okra C. oliterius is consumed by almost every ethnic group, especially in South-West, North Central and Northeastern Nigeria.…”

Section: Introductionmentioning

confidence: 80%

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Phytochemical analysis, proximate composition and antinutritional factors of <i>Corchorus oliterius</i> plant

Sha’a¹,

Clarkson²,

Artimas³

2019

Int. J. Bio. Chem. Sci

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Leafy vegetables play a major in meeting the dietary requirement of an average Nigerian. The knowledge of nutritional and antinutritional properties of these local plant resources therefore becomes necessary. This study was to conduct a phytochemical analysis, determination of proximate composition and antinutritional factors of Corchorus oliterius using standard procedures. The qualitative phytochemical analysis revealed the presence of saponins, terpenoids, flavonoids, alkaloids and phenols. Proximate analysis, which partitioned the nutrients into six components revealed the nutrients, thus, moisture (8.84±0.00%), ash (11.18±0.00%), crude protein (27.32±0.02%), crude fat (5.64±0.01%), and crude fibre (5.84±0.02, and nitrogen free extractives (NFE) (41.16±0.00%). Antintritional factors were recorded, thus; oxalate (241.96±0.0 2mg/100g), saponins (0.68±0.00%), tannins (18.16±0.00 mg/100g), cyanogenic glycosides (2.78±0.01 mg/100g), and phytate (0.80±0.00%). The presence of phytochemicals such as terpenoids, flavonoids alkaloids and phenols validates the use of C. olitrius in traditional and alternative medicines since phytochemicals found in fruits and vegetables are generally known for being responsible for protective health benefits in man and animals. This result showed that the vegetable was a promising source of protein in human diet if well processed. All the concentrations of antinutrients were found to be within acceptable levels for human and animal consumption. However, the levels of antinutrients can be reduced by traditional processing techniques such as boiling, steaming, cooking, to make it safer for human consumption.

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Section: Introductionmentioning

confidence: 80%

“…Phytochemicals are known to function as immunomodulators and may exhibit antioxidant, anti-inflammatory, anticancer, antimalarial and antimicrobial properties (Sadat et al, 2017). Phytochemicals are also referred to as phytonutrients and are classified according to their chemical structures and functional properties.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical analysis, proximate composition and antinutritional factors of <i>Corchorus oliterius</i> plant

Sha’a¹,

Clarkson²,

Artimas³

2019

Int. J. Bio. Chem. Sci

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“…Phytochemical screening showed that the rhizomes of A. africana contain secondary metabolites, in particular triterpenes, tannins, flavonoids, saponins, phenolic compounds (Table 1). These phytochemicals possess therapeutic activity that could justify its uses as traditional medicine [23].…”

Section: Discussionmentioning

confidence: 99%

“…They play an important role in prevention and treatment of chronic diseases including inflammatory processes. It has been known that plant steroid, flavonoids, tannins, and phenols are antioxidants [23,30]. [31,32] have indicated that more than one the measurement of antioxidant capacity is necessary for take into account the different antioxidant modes of action.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical, Antioxidant and Anti-Inflammatory Effects of Extracts from Ampelocissus africana (Lour) Merr (Vitaceae) Rhizomes

Kabré

Ouédraogo

Coulibaly

et al. 2020

JPRI

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Aims: To determine the phytochemical composition and evaluate the antioxidant and anti-inflammatory properties of methanolic and aqueous extracts from Ampelocissus africana (Lour) Merr rhizomes. Study Design: Phytochemical content and screening, in vitro antioxidant and anti-inflammatory assays. Place and Duration of Study: Department of Traditional Pharmacopoeia and Pharmacy (MEPHATRA / PH) of the Institute for Research in Health Sciences (IRSS) and Laboratory of Applied Biochemistry and Chemistry (LABIOCA), University Joseph KI-ZERBO in Ouagadougou between April and August 2020. Methodology: The antioxidant activity of both extracts of the plant was assessed using DPPH radical scavenging, ABTS+ radical cation decolorization, ferric ion reduction and lipid peroxidation inhibition in rat liver assays. The anti-inflammatory activities in vitro were measured on the ability of the extract to inhibit the activity of enzymes such as 15-lipoxygenase, phospholipase A2 (PLA2) and cyclooxygenases (COX-1 and COX-2). Results: This study revealed that the total phenolic contents of the extracts varied from 471.79 ± 1.71 mg GAE/g to 173.88 ± 1.71 mg GAE/g for methanolic and aqueous extract respectively. The extracts were also rich in flavonoids and tannins. The methanolic extract possessed better antioxidant activity with an IC50 of 2.32 ± 0.18 µg/ml for the ABTS, 1.71 ± 0.05 µg/mL for the DPPH, a reducing power agent of 87.44 ± 0.5 mmol AAE /100 g and a percentage inhibition of lipid peroxidation of 52.21%. The methanolic and aqueous extract of A. africana has an inhibitory action on activity of lipoxygenase with IC50 values of 26.09 ± 1.83 μg/mL to 34.32 ± 1.60 μg/mL, respectively. The methanolic extract caused COX-1 inhibition of 36.07%, COX-2 inhibition of 38.31% and PLA2 inhibition of 26.9%. Conclusion: These results showed that the methanolic and aqueous extract from the rhizomes of Ampelocissus africana possessed antioxidant power, inhibitor effect against proinflammatory enzymes.

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“…However, our results differ from those of some authors such as Qorina et al, (2019) who demonstrated the presence of alkaloids and gall tannins from the extract of Annona muricata leaves using other solvents (ethanol, methanol, n-hexane and ethyl acetate). In addition, the presence of alkaloids is also noted in the methanolic extract of the leaves of Corchorus olitorius (Sadat et al, 2017). These secondary metabolites have many biological and therapeutic properties.…”

Section: Qualitative Phytochemical Screeningmentioning

confidence: 99%

Phytochemical Study and Antioxidant Activity of Annona muricata (Annonaceae) and Corchorus olitorius (Tiliaceae) Two Medicinal Plants from the Ivorian Pharmacopoeia Used in the Treatment of Diabetes

Okou¹,

Tra²,

J.Djaman³

et al. 2021

Int.J.Curr.Res.Aca.Rev.

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Annona muricata and Corchorus olitorius are two medicinal plants whose leaves are widely used in Ivory Coast both in nutrition and for the treatment of various pathologies because of their phytochemical compositions. The objective of this study was to determine the phytochemicals and to assess the antioxidant property of the leaves of these two plants. The phytochemical study was carried out using tests for the identification and quantification of phytoconstituents. As for the study of antioxidant activity, it was carried out by measuring the anti-free radical activity either by ABTS or by DPPH. Qualitative phytochemical screening revealed the presence of flavonoids, polyphenols, saponins, sterols, catechetical tannins and terpenes. The quantitative phytochemical screening of the extracts showed that the content of flavonoids (329.10 ± 2.51 mg Eq quercetin/Kg) and that of polyphenols (82.09 ± 0.13 mg Eq gallic acid/g) of Annona muricata are higher than the content of flavonoids (178.45 ± 1.09 mg Eq quercetin/Kg) and that of polyphenols (67.98 ± 5.22 mg Eq gallic acid/g) of Corchorus olitorius. The results of the antioxidant activity by measurement of the ABTS radical shows that the aqueous extract of Annona muricata exhibits the best activity with an IC50 value of 1.79 ± 0.15 μM, while the aqueous extract of Corchorus olitorius records an IC50 value of 2.64 ± 0.05 μM. Similar results are observed with the measurement of DPPH. The various metabolites demonstrated have various therapeutic properties which may be involved in the treatment of diabetes. This would confirm the therapeutic use reported by the populations. However, the evaluation of the antimalarial, antibacterial and anti-inflammatory activities as well as the toxicity test of the aqueous extract of these plants would be necessary.

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Phytochemical Analysis and Antioxidant Activity of Methanolic Extract of Leaves of Corchorus Olitorius

Cited by 19 publications

References 1 publication

Phytochemical analysis, proximate composition and antinutritional factors of <i>Corchorus oliterius</i> plant

Phytochemical analysis, proximate composition and antinutritional factors of <i>Corchorus oliterius</i> plant

Phytochemical, Antioxidant and Anti-Inflammatory Effects of Extracts from Ampelocissus africana (Lour) Merr (Vitaceae) Rhizomes

Phytochemical Study and Antioxidant Activity of Annona muricata (Annonaceae) and Corchorus olitorius (Tiliaceae) Two Medicinal Plants from the Ivorian Pharmacopoeia Used in the Treatment of Diabetes

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