Phytochemical analysis and comparative study of antibacterial effect of turmeric extracts using different solvent.

Basak, Piyali; Adhikary, Tathagata; Das, Pratik; Biswas, Soumyajit

doi:10.1088/1757-899x/410/1/012018

Cited by 5 publications

(3 citation statements)

References 5 publications

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“…This can be explained by the higher presence of phenols, tannins, sterols, and flavonoids in EE extracts. A direct correlation between the summary content of phenols and flavonoids and antibacterial activity of different plant extracts has been reported [ 38 ].…”

Section: Discussionmentioning

confidence: 99%

Antibacterial and Anti-Inflammatory Potential of Polyherbal Formulation Used in Chronic Wound Healing

Mandrika

Kumar

Zandersone

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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Objective. Polyherbal formulations Jathyadi Thailam and Jatyadi Ghritam (JT) are used in Indian traditional medicine for diabetic chronic wounds, fistula, fissure, eczema, and burn management. We aimed to investigate the antibacterial and anti-inflammatory properties of crude hexane and ethanol extracts of JT formulations. Methods. Antibacterial activity of JT extracts was tested to estimate minimum inhibitory concentrations (MICs) against nine reference bacterial strains, including one methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant (MDR) Pseudomonas aeruginosa, and clinical strains of methicillin-susceptible S.aureus (MSSA), all involved in diabetic foot infection. The anti-inflammatory activity of plant extracts was evaluated in LPS-treated macrophage cells by measuring the mRNA levels and secretion of inflammatory mediators. Results. The antibacterial activity of JT extracts was higher against Gram (+) bacteria, with the MICs varying from 1.95 to 62.5 mg/mL. Gram (−) bacteria were only susceptible to ethanol extracts of JT. Plant extracts were found to be the most active against the reference and clinical strains of MSSA, MRSA, and biofilm-forming S. epidermidis. JT extracts efficiently inhibited in a dose-dependent manner the mRNA expression and protein secretion of proinflammatory cytokines IL-6 and IL-1β, and chemokines MCP-1 and CXCL10 in LPS-challenged macrophages. Conclusion. In the present study, we have shown that extracts of JT formulations possess potent antibacterial and anti-inflammatory properties that could be involved in chronic wound healing activity and has the potential to be used as external add-on therapy in the management of multidrug-resistant bacterial infections at the wound.

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Section: Discussionmentioning

confidence: 99%

Antibacterial and Anti-Inflammatory Potential of Polyherbal Formulation Used in Chronic Wound Healing

Mandrika

Kumar

Zandersone

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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“…(2016) melaporkan bahwa kunyit dapat digunakan sebagai pengganti antibiotik sintetik karena mengandung senyawa bioaktif yang mampu menekan mikroba patogen pada ayam broiler. Senyawa kurkumin pada kunyit dilaporkan memiliki sifat antimikroba (Basak et al, 2018) dan antibakteri patogen (Feghali et al, 2018). Halimatunnisroh dkk.…”

Section: Kata Kunciunclassified

TOTAL BAKTERI ASAM LAKTAT DAN COLIFORM USUS ITIK CIHATEUP YANG DIBERI PAKAN MENGANDUNG KOMBINASI TEPUNG KULIT MANGGIS DAN KUNYIT (Total Lactic Acid Bacteria and Coliform of Cihateup Ducks Intestine that Given Feed Containing the Combination of Mangosteen Peel and Turmeric Flour)

Kusmayadi

Rahayu

2020

JITP

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The number of beneficial microbial populations (lactic acid bacteria/LAB) and pathogens (coliform) in the digestive tract of ducks is one indicator of duck health status. Healthy ducks have a beneficial microbial population more than pathogenic bacteria. The addition of herbal ingredients such as mangosteen peel and turmeric flour is thought to improve the health of ducks by increasing the LAB population. The purpose of this study was to examine the effect of the combination of mangosteen peel flour and turmeric flour on the total lactic acid bacteria and coliform of small intestine and caecum of Cihateup duck. The study was conducted experimentally using 60 male Cihateup ducks grouped into 5 feed treatments which contains a combination of mangosteen peel and turmeric flour at different levels as follows: 0.5% (R1); 1.0% (R2); 1.5% (R3); 2.0% (R4); and 2.5% (R5), respectively. The variables studied were total lactic acid and coliform bacteria in the small intestine and caecum of Cihateup ducks. The results showed that the treatments of feed significantly (P<0.05) affected the total lactic acid bacteria (except caecum) and coliform bacteria. The population of lactic acid bacteria tended to increase along with the increasing dose of combination treatment of mangosteen peel and turmeric flour. In contrast, the total population of coliform bacteria in the small intestine and caecum of ducks showed a tendency to decrease with increasing treatment doses. The use of a combination of mangosteen peel and turmeric flour at higher levels (2.0 – 2.5%) can increase the total LAB and decrease coliform bacteria in the small intestine and cecum of Cihateup duck.

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“…Furthermore, Natsir et al (2016) added that turmeric contains bioactive compounds capable of suppressing pathogenic microbes in broiler chickens. The curcumin compound in turmeric is reported to have antimicrobial (Basak et al, 2018) and antibacterial properties (Feghali et al, 2018). In addressing the highly complex feed problem in Sukanagalih Village, the implementation of appropriate technology programs is necessary by processing supplementary feed using mangosteen peel and turmeric as raw materials to produce affordable, efficient, and safe supplementary feed for livestock and humans as consumers.…”

Section: Introductionmentioning

confidence: 99%

Application of appropriate technology for feed supplements in Sukanagalih Village, Tasikmalaya Regency

Kusmayadi,

Achmad,

Sumaryana

et al. 2024

ABDIMAS J. Pengabdi. Masy. Univ. Merdeka Malang

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Feed supplement is useful as a growth promoter, increasing efficiency and feed consumption, helping digestion and metabolism, and improving the quality of livestock products. The aim of this community service is to apply appropriate technology to utilize mangosteen peel and turmeric as feed supplement for poultry in Sukanagalih Village, Tasikmalaya Regency, as well as produce quality feed supplement and improve the skills of farmers in processing the supplement feed. This community service activity is one of the Kosabangsa programs between the Universitas Perjuangan Tasikmalaya as the implementation team and the IPB University as the accompanying team. This activity started from September to December 2023 in Sukanagalih Village, Rajapolah District, Tasikmalaya Regency. The method for implementing this activity consists of counseling, training, and assistance to livestock groups. The target partners for this activity were Kelompok Megar Bebek Cihateup and the Berdikari Village-Owned Enterprise (Bumdes Berdikari) with a total of 20 participants each, so the total participants are 40 people. The level of community empowerment increased to 80 – 85% in the knowledge, skills, accessibility, and income categories. The results of this activity are very beneficial for the community, where the application of appropriate technology for processing mangosteen peel and turmeric as feed supplements can increase the added value and selling value of agro-industrial waste products in Tasikmalaya Regency. The application of appropriate technology for the use of supplement feed is able to increase the knowledge and skills of the community in Sukanagalih Village, Tasikmalaya Regency in processing feed supplements.

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Phytochemical analysis and comparative study of antibacterial effect of turmeric extracts using different solvent.

Cited by 5 publications

References 5 publications

Antibacterial and Anti-Inflammatory Potential of Polyherbal Formulation Used in Chronic Wound Healing

Antibacterial and Anti-Inflammatory Potential of Polyherbal Formulation Used in Chronic Wound Healing

TOTAL BAKTERI ASAM LAKTAT DAN COLIFORM USUS ITIK CIHATEUP YANG DIBERI PAKAN MENGANDUNG KOMBINASI TEPUNG KULIT MANGGIS DAN KUNYIT (Total Lactic Acid Bacteria and Coliform of Cihateup Ducks Intestine that Given Feed Containing the Combination of Mangosteen Peel and Turmeric Flour)

Application of appropriate technology for feed supplements in Sukanagalih Village, Tasikmalaya Regency

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