Phytochemical analysis, antimicrobial screening and hypoglycemic effect of some selected medicinal plant extract from Oman

Abstract

In present study phytochemical screening and antimicrobial potential of three Omani traditional medicinal plants i.e. Ajuga iva, Pteropyrum scoparium and Rhazya stricta was carried out. The information generated from study will be helpful in drug administration and developing commercial drug form these studied traditional plants. All three selected plants were air dried under natural condition and phytochemical screenings were carried out under laboratory conditions. Antimicrobial properties of the selected plants were carried out against the selected microorganisms i.e. Bacteria (E.coli, Staphylococcus and Bacillus species) and fungi (Trichoderma and Aspergillus). Further, selected plants were also used to test their effect on reducing diabetic incidence. Results of study revealed that selected plants have significant inhibitory effect on the multiplication of selected microorganisms. Similarly oral administration of plant extract also reduced the blood sugar level of the treated mice; it started reducing after 1 week of treatment and continued till 21 days of exposure as compared to control. Further, phytochemical screening of these plants indicated that these plants contain many of chemical substances which had important role in the reducing blood sugar level.

Middle East Medicinal Plants in the Treatment of Diabetes: A Review

“…The results of the study revealed that the selected plants had reduced the blood sugar level of the treated mice; the extracts of R. stricta and A. iva had more pronounced effects than P. scoparium . The hypoglycemic effect of R. stricta extract may be due to its potentiating effect on the insulin-releasing mechanism; this suggests a mode of action resembling the mechanism of sulfonylureas [ 25 ].…”