Phytochemical and antimicrobial study of Chukrasia tabularis leaves

Nagalakshmi, M. A. H.; Thangadurai, Devarajan; Rao, D Muralidara; Pullaiah, T.

doi:10.1016/s0367-326x(00)00245-8

Cited by 30 publications

(17 citation statements)

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“…Nonato et al [19] confirmed the antinociceptive and anti-inflammatory activities of A. latifolium. Amrutha Lakshmi [20] also confirmed the antimicrobial properties of A. latifolium. Compounds derived from A. lunulatum have been shown antibacterial activity against Gram positive and negative bacteria [21] and anti-fertility on reproductive organs of male albino rats.…”

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confidence: 57%

Antibacterial Potentials of Adiantum Species against the UTI Pathogens

Johnson

Jeevas

Mahesh

et al. 2017

JMEN

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The present study was aimed to screen the anti-bacterial properties of medicinally important ferns viz., Adiantum caudatum L., Adiantum latifolium Lam. and Adiantum lunulatum Burm against the selected UTI pathogens. Anti-bacterial study was carried out by disc diffusion method against the pathogens viz., Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus maximum degree of antibacterial activity was observed in A. latifolium followed by A. caudatum whereas A. lunulatum showed comparatively less degree of antibacterial activity. Further work will accentuate the isolation and characterization of active principles responsible for bio-efficacy.

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confidence: 57%

Antibacterial Potentials of Adiantum Species against the UTI Pathogens

Johnson

Jeevas

Mahesh

et al. 2017

JMEN

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“…Swietenia mahagoni seeds have been applied as folk medicine for the treatment of hypertension, diabetes, and malaria. [3] The seeds have also been reported to have medicinal value for treatment of cancer, amoebiasis, cough, chest pain, and intestinal parasitism. However the claim that Swietenia mahagoni seeds extract safe usage in folk medicine is unsubstantiated by scientific studies.…”

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confidence: 99%

Brine shrimp lethality and acute oral toxicity studies on Swietenia mahagoni (Linn.) Jacq. seed methanolic extract

et al. 2010

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Background:The seeds of Swietenia mahagoni have been applied in folk medicine for the treatment of hypertension, diabetes, malaria, amoebiasis, cough, chest pain, and intestinal parasitism. Here we are the first to report on the toxicity of the Swietenia mahagoni crude methanolic (SMCM) seed extract.Methods:SMCM seed extract has been studied for its brine shrimp lethality and acute oral toxicity, in mice.Results:The brine shrimp lethality bioassay shows a moderate cytotoxicity at high concentration. The LC50 for the extract is 0.68 mg/ml at 24 hours of exposure. The LD50 of the SMCM seed extract for acute oral toxicity in mice is greater than 5000 mg/kg.Conclusion:This study demonstrates that Swietenia mahagoni crude methanolic seed extract may contain bioactive compounds of potential therapeutic significance which are relatively safe from toxic effects, and can compromise the medicinal use of this plant in folk medicine.

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“…[9][10][11] Swietenia mahagoni (L.) Jacq. seeds are also reported to have medicinal value for the treatment of hypertension, diabetes, malaria, 12 cancer, amoebiasis, coughs and intertinal parasitism. 13 Furthermore, the seed extract S. mahagoni (L.) Jacq.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial activity of bioactive compounds isolated from Swietenia mahagoni (L) Jacq. against Staphylococcus aureus and Pseudomonas aeruginosa

Darussalam¹,

Nuryastuti

Mursiti

et al. 2014

JMedScie

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Widespread bacterial resistance has led to more difficult to treat infectious diseases with available antibiotics. Therefore, new antibiotics are needed face of the growing antibiotic resistance. Swietenia mahagoni (L.) Jacq. is one of potential medicinal plants as a source new antibiotics. Five compounds have been isolated from an ethanolic extract of S. mahagoni (L.) Jacq., however its antimicrobial activity has not been investigated, yet. This study was conducted to evaluate the antimicrobial activity of these compounds. Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) were determined against Staphylococcus aureus and Pseudomonas aeruginosa strains. Among five compounds tested, compound 3 (3,4,5,6,7-pentaethyl-1-methoxy-1H-indazole) and compound 4 (5-ethyl-6-methoxymethyl-2-methyl-1,2-dihydropyridine) were found to be active against the bactrial strains tested with the MICs and MBCs values ranged from 50 to 100 μg/mL. In conclusion, among five compounds isolated from S. mahagoni (L.) Jacq., compound 3 and 4 showed moderate antimicrobial activity against S. aureus and P. aeruginosa strains. ABSTRAKPenyebaran secara luas resistensi bakteri menyebabkan pengobatan penyakit infeksi menjadi lebih sulit dengan antibiotik yang tersedia. Adanya antibiotik baru dengan demikian diperlukan menghadapi penyebaran resistensi antibiotik tersebut. Swietenia mahagoni (L.) Jacq adalah salah satu tanaman obat yang potensial sebagai penghasil antibiotik baru. Lima senyawa telah diisolasi dari ekstrak etanol biji S. mahagoni (L) Jacq. namun demikian aktivitas antimikrobanya belum dikaji. Penelitian ini bertujuan untuk mengkaji aktivitas antimikroba ke lima senyawa hasil isolasi tersebut. Kadar Hambat Minimal (KHM) dan Kadar Bunuh Minimal (KBM) ditetapkan terhadap strain Staphylococcus aureus and Pseudomonas aeruginosa. Diantaran lima senyawa yang diuji, senyawa 3 (3,4,5,6,7-pentaetil-1-metoksi-1H-indazol) dan 4 (5-etil-6-metoksimetil-2-metil-1,2-dihidropiridin) aktif terhadap strain bakteri yang diuji dengan nilai KHM dan KBM antara 50 sampai 100 μg/mL. Dapat disimpulkan, diantaran lima senyawa yang diisolasi dari S. mahagoni (L.) Jacq. senyawa 3 dan 4 mempunyai aktivitas antimikroba moderat terhadap strain S. aureus and P. aeruginosa.

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Phytochemical and antimicrobial study of Chukrasia tabularis leaves

Cited by 30 publications

References 1 publication

Antibacterial Potentials of Adiantum Species against the UTI Pathogens

Antibacterial Potentials of Adiantum Species against the UTI Pathogens

Brine shrimp lethality and acute oral toxicity studies on Swietenia mahagoni (Linn.) Jacq. seed methanolic extract

Antimicrobial activity of bioactive compounds isolated from Swietenia mahagoni (L) Jacq. against Staphylococcus aureus and Pseudomonas aeruginosa

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