Phytochemical and Biological Properties of Lippia gracilis

Moraes, Valéria Regina de Souza; Nogueira, Paulo César de Lima; Costa, Emmanoel V.; Santos, Luciano de S.; Silva, Valdenizia Rodrigues; Bomfim, Larissa M.; Bezerra, Daniel P.

doi:10.1007/978-981-10-8548-2_2

Cited by 3 publications

(4 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These percentages agree with the compositions identified in the HPLC-DAD-ESI-MS n analysis. Many studies presented in the literature data, with chemical compositions similar to those presented in this manuscript, have reported the significant antioxidant activity of L. alba, L. gracilis, and L. sidoides [43,49,54].…”

Section: Chemical Compositionsupporting

confidence: 59%

“…The chemical compositions of the ethanolic extract of Lippia species showed an abundance of secondary metabolites of the flavonoids class [45], corroborating with the results of this study. The flavonoids apigenin-7-O-glucuronide (22), tricin-7-O-glucuronide (21), isorhamnetin (27), and naringenin appear in different extracts of L. alba [39,43,47], as well as taxifolin (8), luteolin, naringenin, and apigenin (30) in L. sidoides [48] and naringenin, quercetin (25), orientin (10), and isoorientin (11) in L. gracilis [49]. The diglycosylated form of the flavone chrysoeriol (29) has also been reported for L. alba [41].…”

Section: Chemical Compositionmentioning

confidence: 99%

See 1 more Smart Citation

Antibacterial Activity and Anxiolytic Effect in Adult Zebrafish of Genus Lippia L. Species

Nonato

Melo

Camilo

et al. 2023

Plants

View full text Add to dashboard Cite

Species belonging to the genus Lippia are used worldwide as foods, beverages, and seasonings. Studies have demonstrated that these species have antioxidant, sedative, analgesic, anti-inflammatory, and antipyretic activities. This work aimed to evaluate the antibacterial activity and anxiolytic effect by different pathways of essential oils and ethanolic extracts of three species of Lippia (Lippia alba, Lippia sidoides, and Lippia gracilis). The ethanolic extracts were characterized by HPLC-DAD-ESI-MSn and their phenolics were quantified. The antibacterial activity was evaluated by determining the minimal inhibitory concentration and modulation of antibiotic activity, and toxic and anxiolytic effects were evaluated in the zebrafish model. The extracts showed compositions with a low ratio and shared compounds. L. alba and L. gracilis showed higher amounts of phenols and flavonoids, respectively. All extracts and essential oils presented antibacterial activity, especially those obtained from L. sidoides. On the other hand, L. alba extract presented the most significant antibiotic-enhancing effect. The samples were not toxic after 96 h of exposure, but showed an anxiolytic effect through modulation of the GABAA receptor, while L. alba extract acted via modulation of the 5-HT receptor. This new pharmacological evidence opens horizons for therapeutic approaches targeting anxiolytic and antibacterial therapies and food conservation using these species and their constituents.

show abstract

Section: Chemical Compositionsupporting

confidence: 59%

Section: Chemical Compositionmentioning

confidence: 99%

Antibacterial Activity and Anxiolytic Effect in Adult Zebrafish of Genus Lippia L. Species

Nonato

Melo

Camilo

et al. 2023

Plants

View full text Add to dashboard Cite

show abstract

“…Entre os muitos OEs conhecidos, o OE de alecrim-pimenta se destaca por conter em sua estrutura, uma grande quantidade dos monoterpenos aromáticos, timol e carvacrol, que por sua vez, apresentam notórias características farmacológicas (Simões et al, 2004, Saraiva et al, 2020. O carvacrol 2-metil-5-(1-metiletil)-fenol e seu isômero timol 5metil-2-(1-metiletil)-fenol são biossintetizados a partir do γ-terpineno e do ρ-cimeno (Nostro;Papalia, 2012;de Souza et al, 2018). Similares estruturalmente, variando apenas a posição do grupo hidroxila no anel fenólico.…”

Section: Introductionunclassified

Condições ambientais e horário da coleta influenciam na produção do óleo essencial das folhas de Lippia sidoides no litoral cearense

Júnior¹,

Filho²,

Amoni³

et al. 2022

RSD

View full text Add to dashboard Cite

A literatura aponta que além das influências como temperatura, umidade e técnicas de cultivo, outras variáveis interferem na produção de óleos essenciais por plantas aromáticas, destacando-se a sazonalidade e ciclo circadiano próprio da planta. Este estudo tem como objetivo avaliar a influência das condições ambientais e do horário da coleta na produção de óleos essenciais das folhas do Alecrim-pimenta (Lippia sidoides Cham.). As folhas foram coletadas em outubro-novembro/2019 no horto de plantas medicinais da Faculdade do Vale do Jaguaribe, Aracati-Ceará. A coleta foi inteiramente casualizada e dividida em quatro horários (6:00, 10:00, 14:00 e 18:00), com quatro repetições e em duplicatas. A análise estatística foi realizada empregando-se o teste T de Student, considerando p < 0.05. As amostras apresentaram menor umidade (60,5%) às 10h, em contrapartida, 6h foi verificada uma maior umidade (64,1%). As análises mostraram que as maiores quantidades de óleo essencial, em termos relativos, foram produzidas às 10h (20,8%). A temperatura ambiente apresentou uma relação positiva com o peso da folha seca e negativa com a umidade da folha. Dessa forma, foi possível verificar que os teores de óleo essencial são influenciados por diferentes variáveis, recomendando-se a colheita às 10h.

show abstract

“…O alecrimde-tabuleiro é uma planta nativa do nordeste brasileiro e possui utilização como planta medicinal. Sua utilização popular é relatada no tratamento de seborreia, dermatoses, acne e infecções na garganta (Moraes et al, 2018).…”

Section: Introductionunclassified

Cinética de Secagem e Equilíbrio Higroscópico de Folhas de Alecrim-de-tabuleiro

Moreira

Andrade

Rios

et al. 2020

RSD

View full text Add to dashboard Cite

The medicinal plants of genus Lippia is used worldwide for its medicinal characteristics. However, there is a need to study the drying kinetics and hygroscopic balance of Lippia gracilis leaves by varying the drying temperature. The objective of this work was to study the drying kinetics of Lippia gracilis as well as to adjust a model among those existing in the literature that best represents the behavior of the sorption isotherm. The rosemary leaves were processed and submitted to drying air temperatures of 40, 50, 60, and 70 ºC in a fixed layer mechanical dryer. For the study of the hygroscopic phenomenon, temperatures of 20, 30, 55, and 70 ºC were used with water activities between 0.11 and 0.81. The model that best represented the drying curves was the Midilli model with an R² of 99.60. The model that best represented the hygroscopic balance curve of Lippia gracilis was that of Sabbah with an R² of 93.33%.

show abstract

Phytochemical and Biological Properties of Lippia gracilis

Cited by 3 publications

References 40 publications

Antibacterial Activity and Anxiolytic Effect in Adult Zebrafish of Genus Lippia L. Species

Antibacterial Activity and Anxiolytic Effect in Adult Zebrafish of Genus Lippia L. Species

Condições ambientais e horário da coleta influenciam na produção do óleo essencial das folhas de Lippia sidoides no litoral cearense

Cinética de Secagem e Equilíbrio Higroscópico de Folhas de Alecrim-de-tabuleiro

Contact Info

Product

Resources

About