Phytochemical and Pharmacological Evaluation of Ethanol Leaves Extract of Hydnocarpus kurzii (King) Warb

Abstract

Mankind has always depended on medicinal plants for eradication and management of diseases. Hydnocarpus kurzii-a medicinal plant from Achariaceae family, is cultivated in areas of Southeast Asia, tropical Africa and tropical South America. In Bangladesh, it is commonly found in the Chittagong Hill Tracts, Cox's Bazar, Moulavi Bazar, Mymensingh and locally known as Chaulmoogra. H. kurzii is a 12-15 meter tall evergreen, dioecious tree. The lanceolate leaves are 18-25 cm long. The reddish brown fruits are orange shaped. 1,2 The main medicinal ingredient-chaulmoogra is extracted from the seeds which are used to treat different types of diseases such as scabies, eczema, psoriasis, scrofula, ringworm, and intestinal parasitic worms. 2 Besides the oil, its leaves, fruits and barks are also used in the traditional medicinal system for their analgesic, purgative, antioxidant, antidiabetic, haematinic and cytotoxic properties. 2 Different cyclopentenyl fatty acid derivatives such as hydnocarpic acid, chaulmoogric acid, gorlic acid along with oleic acid, palmitic acid, myristic acid, stearic acid, palmitoleic acid, linoleic acid, linolenic acids, gallic acid, hydnocarpin were isolated from various parts of this plant. 1,3 Following the review of its traditional uses, we selected its leaves to quantify the antioxidative components, radical scavenging properties and evaluate its different

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