Phytochemical and pharmacological properties of Myristica fragrans Houtt.: an updated review

Ha, Manh Tuan; Vu, Ngoc Khanh; Trần, Thu Hương; Kim, Jeong Ah; Woo, Mi Hee

doi:10.1007/s12272-020-01285-4

Cited by 64 publications

(54 citation statements)

References 95 publications

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“…Plant constituents present in Myristica fragrans are myristicin, elemicin, eugenol, dehydriisoeugenol and myristic acid. Recent studies on nutmeg exerts many pharmacological activities such as antiin ammatory, antipyretic, anthelmintic, digestive, antispasmodic, narcotic, anticonvulsant, antiseptic, constipating and tonic, antihepatotoxic, anticancer, antidepressant, hypolipidemic and antifungal etc [12] .…”

Section: Introductionmentioning

confidence: 99%

Anti-Diabetic Activity of Silver Nanoparticles Synthesized from the Hydroethanolic Extract of Myristica fragrans Seeds

Perumalsamy

Krishnadhas

2022

Appl Biochem Biotechnol

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Myristica fragrans, also known as nutmeg is a spice that cures various diseases. This study aimed to synthesize silver nanoparticles from a hydroethanolic extract of Myristica fragrans seeds (MFHE) and evaluate their anti-diabetic properties. To MFHE, AgNO 3 solution was added and exposed to sunlight to produce silver nanoparticles from hydroethanolic seed extract of Myristica fragrans (MFHENP). The MFHENP was characterized by numerous techniques. UV-visible spectroscopy con rmed the formation of silver nanoparticles by the absorption peak at 430nm. Scanning electron microscopy (SEM) studies revealed the shape and size of the particles at the range of 50-60nm. Energy-dispersive X-ray spectroscopy (EDX) disclosed the presence of silver ions. X-ray diffraction spectrum con rmed the crystalline nature of silver nanoparticles by the peak at 39 o . FTIR analysis revealed the functional groups present in MFHE as well as in MFHENP and Zeta potential analysis was found to be 14mV. Furthermore, in-vitro anti-diabetic activity was investigated. MFHENP showed signi cant e ciency against the inhibition of alpha-amylase and alpha-glucosidase enzymes and also MFHENP retarded the glucose transport across the membrane which is analyzed by glucose diffusion and glucose uptake assays.Acarbose is used as a standard for all these methods and MFHENP e ciency proves their therapeutic potential for the treatment of diabetes mellitus.

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Section: Introductionmentioning

confidence: 99%

Anti-Diabetic Activity of Silver Nanoparticles Synthesized from the Hydroethanolic Extract of Myristica fragrans Seeds

Perumalsamy

Krishnadhas

2022

Appl Biochem Biotechnol

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“…Ginger has been used in medicine as anti-microbial, anti-pyretic, analgesic, anti-inflammatory, hypoglycaemic, anti-ulcer, anti-emetic, anti-hypertensive, hypolipidemic effects (Shahrajabian, Sun & Cheng, 2019). Nutmeg, the dried seed kernel of Myristica Fragrans, has been used as spice which exhibits many pharmacological activities such as anti-inflammatory, analgesic, antioxidant, antibacterial, antidiabetic and anticancer activities (Ha, Vu, Tran, Kim, Woo, & Min, 2020). Turmeric, the rhizome of Curcuma longa, has been used as a spice and medical herb due to its antioxidant, anti-inflammatory, antimutagenic, antimicrobial, and anticancer properties (Hewlings, & Kalman, 2017).…”

Section: Introductionmentioning

confidence: 99%

Assessment of toxic metals in commonly used herbs and spices in Turkey

Özden¹

2021

ijp

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Background and Aims:The levels of cadmium (Cd) and lead (Pb) were analyzed in frequently used herbs including ginger, liquorice, nutmeg and turmeric in Turkey. Materials and Methods:The levels of Cd and Pb in commonly used herbs were analyzed by inductively coupled plasma optical emission spectrometry after a closed microwave-assisted digestion. Results: The concentration ranges for the Cd and Pb were found to be 0.25-0.78 mg/kg and 3.04-6.45 mg/kg, respectively. While Pb levels were below the maximum permissible limits, high Cd levels were detected in herbs which would not pose any health risk for consumers regarding an exposure assessment. Conclusion:It is important to implement regular monitoring of heavy metal content in herbs, including medicinal plants, to assess their potential risks to human health in consideration of the potential for multiple exposure via other sources.

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“…Another study revealed that nutmeg essential oil contains phenylpropanoid compounds, such as trimyristin, myristic acid, myristicin, and eugenol (Ha et al, 2020). Eugenol is a well-known antioxidant and anti-inflammatory agent and demonstrates antimicrobial activity against a wide range of both Gram-positive and Gram-negative bacteria (Daniel et al, 2009;Gülçin, 2011;Hu et al, 2018;Sanla-Ead et al, 2012).…”

Section: Myristica Fragrans (Nutmeg) Extractmentioning

confidence: 99%

Promising strategies to control persistent enemies: Some new technologies to combat biofilm in the food industry—A review

Mevo

Ashrafudoulla

Mizan

et al. 2021

Comp Rev Food Sci Food Safe

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Biofilm is an advanced form of protection that allows bacterial cells to withstand adverse environmental conditions. The complex structure of biofilm results from genetic-related mechanisms besides other factors such as bacterial morphology or substratum properties. Inhibition of biofilm formation of harmful bacteria (spoilage and pathogenic bacteria) is a critical task in the food industry because of the enhanced resistance of biofilm bacteria to stress, such as cleaning and disinfection methods traditionally used in food processing plants, and the increased food safety risks threatening consumer health caused by recurrent contamination and rapid deterioration of food by biofilm cells. Therefore, it is urgent to find methods and strategies for effectively combating bacterial biofilm formation and eradicating mature biofilms. Innovative and promising approaches to control bacteria and their biofilms are emerging. These new approaches range from methods based on natural ingredients to the use of nanoparticles. This literature review aims to describe the efficacy of these strategies and provide an overview of recent promising biofilm control technologies in the food processing sector.

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Phytochemical and pharmacological properties of Myristica fragrans Houtt.: an updated review

Cited by 64 publications

References 95 publications

Anti-Diabetic Activity of Silver Nanoparticles Synthesized from the Hydroethanolic Extract of Myristica fragrans Seeds

Anti-Diabetic Activity of Silver Nanoparticles Synthesized from the Hydroethanolic Extract of Myristica fragrans Seeds

Assessment of toxic metals in commonly used herbs and spices in Turkey

Promising strategies to control persistent enemies: Some new technologies to combat biofilm in the food industry—A review

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