Phytochemical, antioxidant and antimicrobial properties of Litsea angulata extracts

Abstract

Background: Litsea angulata is a plant species belonging to Lauraceae family that is distributed throughout Indonesia, Malaysia, and New Guinea. The seeds have been traditionally used by local people in Kalimantan, Indonesia for the treatment of boils; however, there is no information about the potency of its branch, bark and leaves yet. This study aimed to determine the antioxidant, antimicrobial activity as well as the phytochemical constituent of Litsea angulata branch, bark, and leaves. Methods: Extraction was performed by successive maceration method using n-hexane, ethyl acetate, and ethanol solvent. Antioxidant activity was evaluated by DPPH radical scavenging assay. The antimicrobial activity using the 96 well-plate microdilution broth method against Staphylococcus aureus and Streptococcus mutans. Results: Based on the phytochemical analysis, it showed that extract of L. angulata contains alkaloids, flavonoids, tannins, terpenoids, and coumarin. The results showed that all extracts of plant samples displayed the ability to inhibit DPPH free radical formation and all tested microorganisms. Conclusions: L. angulata contains secondary metabolites such as alkaloids, flavonoids, tannins, terpenoids, carotenoids, and coumarin. The antioxidant activity on different plant extracts was a range as very strong to weak capacity. All extracts in this study could inhibit the growth of S. aureus and S. mutans.

Litsea cubeba essential oil: Extraction, chemical composition, antioxidant and antimicrobial properties, and applications in the food industry

“…Kuspradini et al. (2018) determined the antioxidant activity of Litsea angulata branches, bark, and leaves. Chakraborty and Mandal (2018) analyzed the antioxidants and free radical scavenging activity of sequential extraction with solvents of gradient polarity from fresh L. cubeba fruits.…”

Efektifitas Biji Kalangkala (Litsea angulata) dan Daun Kelakai (Stenochlaena palustris (BURM. F.) BEDD.) terhadap Daya Hambat Bakteri P. Aeruginosa Pada Luka Dekubitus

“…Menurut studi, kalakai mempunyai efek anti oksidan yang sangat kuat dan memiliki kandungan metabolit seperti alkaloid, flavonoid, phenol, saponin, terpenoid, dan tanin yang memiliki manfaat sebagai antimikroba dan berefek baik terhadap luka (9,12,14) Tumbuhan lain yang mengandung fitokimia yang berfungsi sebagai antibakteri adalah biji kalangkala. Kalangkala merupakan tanaman yang tumbuh subur di Kalimantan, sebagian masyrakat Kalimantan menggunakan biji kalangkala secara tradisional untuk mengobati bisul (15). Ekstrak kalangkala merupakan bahan alami dilaporkan memiliki banyak aktivitas biologis kandungan fitokimia, yang memberikan kontribusi signifikan terhadap aktivitas antioksidan dan antimikroba seperti flavonoid, tanin, dan terpenoid (10).…”