Phytochemical Constituents, Health Benefits, and Industrial Applications of Grape Seeds: A Mini-Review

Abstract

Grapes are one of the most widely grown fruits and have been used for winemaking since the ancient Greek and Roman civilizations. Grape seeds are rich in proanthocyanidins which have been shown to possess potent free radical scavenging activity. Grape seeds are a complex matrix containing 40% fiber, 16% oil, 11% proteins, and 7% complex phenols such as tannins. Grape seeds are rich sources of flavonoids and contain monomers, dimers, trimers, oligomers, and polymers. The monomeric compounds includes (+)-catechins, (−)-epicatechin, and (−)-epicatechin-3-O-gallate. Studies have reported that grape seeds exhibit a broad spectrum of pharmacological properties against oxidative stress. Their potential health benefits include protection against oxidative damage, and anti-diabetic, anti-cholesterol, and anti-platelet functions. Recognition of such health benefits of proanthocyanidins has led to the use of grape seeds as a dietary supplement by the consumers. This paper summarizes the studies of the phytochemical compounds, pharmacological properties, and industrial applications of grape seeds.

Influence of grape seeds powder on preservation of fats in confectionary glaze

“…The obtained results of chromatographic studies clearly demonstrate that the studied powders from the mixture of grape seeds of different varieties are rich in antioxidants of the phenolic nature. The identified types of polyphenols are in line with the numerous literary sources in terms of the availability of the basic classes of phenolic compounds in the seeds of different grape varieties, determined by the chromatographic methods (for example, [26][27][28][29]) and review publications [11,30,31]. Comparison of the areas of peaks on the chromatograms made it possible to obtain the quantitative relationships between the identified components in both samples.…”

Postorthodontic Relapse Prevention by Administration of Grape Seed (Vitis vinifera) Extract Containing Cyanidine in Rats

“…It contains polyphenolic compounds in the forms of flavan-3-ol, proanthocyanidin (which comprises 90% of grape seed), and catechins. 14,15 Proanthocyanidins and catechins are free radical scavengers required in calcium absorption. One of the proanthocyanidin groups, procyanidin, is primarily found in grape seed and can be transformed into cyanidin through an autooxidation process.…”

Determination of the Chemical Composition of Grape Seed Powders by Gc-MS Analysis

“…The detected phenolic compounds in the isopropyl extract of GSP and DGSF samples are typical for powders of grape seeds of different varieties in other solvents, but in other quantity ratios that is proved by literary sources [7][8][9][10][11][12][13][14][15][16][17][18]. These phenolic compounds are antioxidants [18]. It gives reasons for using grape seed powders as a source of natural antioxidant in food technologies, in first turn -in production of fat-containing confectionary products.…”