Phytochemical Constituents of Some Medicinal Plants in South West, Nigeria

F, Afolabi

doi:10.9790/5736-0417678

Cited by 16 publications

(11 citation statements)

References 8 publications

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“…Phytochemical screening of Annona senegalensis revealed the presence of various secondary metabolites including tannins (Jada et al 2014), flavonoid (Jada et al 2015), saponins (Afolabi & Afolabi 2013), alkaloids (You et al 1995, glycosides, steroids (Ijaiya et al 2014), volatile oil (Ngamo et al 2007), anthocyanins (Mpiana et al 2012), triterpenes and coumarins. GC/MS study of stem bark of A. senegalensis showed the presence of 1, 2 benzenediol, butylated hydroxytoluene (BHT), Phenol, 2, 6 bis (1, 1-dimethylethyl-4methyl, methylcarbamate, n hexadecanoic acid, hexadecane, 13-hexyloxacyclotridec-10-en-2one, oleic acid, tetracosane, 9-octylheptadecane, heneicosane, 12-mehtyl-E, E-2, 13-octadecadien-1-ol, octadecanoic acid, 9, 17-octadecandienal, pentadecane, tetratriacontane and squalene (Awa et al 2012).…”

Section: Phytochemistrymentioning

confidence: 99%

A mini-review on the pharmacognosy and phytochemistry of a tropical medicinal plant: Annona senegalensis Pers. (Annonaceae)

Ngbolua¹,

Moke²,

Baya³

et al. 2017

Trop. Plant Res.

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The aim of this mini-review was to collect data obtained from various studies carried out by different authors concerning the phytochemistry and pharmacognosy of Annona senegalensis (Annonaceae). This review has been compiled using references from major databases such as PubMed, PubMed Central, Science Direct and Google scholars. An extensive survey of literature revealed that A. senegalensis is a good source of health promoting secondary metabolites such as terpenoic acids (kaurenoic acid) among others that could have many wonderful applications (like antisickling properties).Traditionally, the plant is used as stimulant, pain reliever etc. whereas the plant possess beneficial effects such as anti-oxidant, antimicrobial, Antidiarrheal, anti-inflamatory, anti-parasitic, anticonvulsant, antimalarial, anti-trypanosomal, antisnake venom and Antinociceptive and many other medicinal properties. The results of the present review of literature makes A. senegalensis an interesting candidate for advanced anti-sickle cell anemia investigations such as erythroid differentiation and fetal hemoglobin induction effects of this plant using K562 cell lines as model system.

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Section: Phytochemistrymentioning

confidence: 99%

A mini-review on the pharmacognosy and phytochemistry of a tropical medicinal plant: Annona senegalensis Pers. (Annonaceae)

Ngbolua¹,

Moke²,

Baya³

et al. 2017

Trop. Plant Res.

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“…The work of [2] on the leaves of 4 Nigerian medicinal plants namely; Annona senegalensis, Axonopus compressus, Bryophylum pinnatum and Heliotropicum indicum showed that alkaloids, flavonoids, tannins, saponins phenolics were present in all the plants. The result reported the use of these plants for the treatment of various diseases, including; cancer, inflammation, heart diseases, aging, fever reducing, pain relieving due to the presence of flavonoids.…”

Section: Pharmacological Activities Of Nigerian Medicinal Plantsmentioning

confidence: 99%

“…Plants that possess therapeutic properties or exert beneficial pharmacological effects on the human body are generally designated as medicinal plants [1]. A medicinal plant is any plant which in one or more of its organs contains active ingredient which is used for therapeutic purposes or contain foundation compounds that can be used for synthesis of useful drugs [2]. Doughari [3] explained that, medicinal plant is a plant which, in one or more of its organs, contains substances that can be used for therapeutic purposes or which are precursors for chemo-pharmaceutical semi synthesis.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Compositions in Some Nigerian Medicinal Plants and Their Pharmacological Properties: A Review

Kutama¹,

Abdulkadir²,

Kwalli³

et al. 2018

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Nigeria is naturally blessed with both savannah and tropical rainforests vegetation and these offer a wide distribution of plants believed to possesses secondary metabolites which are responsible for treating or curing various diseases. Several researches have been carried out in order to explore and identify the chemical compositions responsible for various pharmacological activities in Nigerian medicinal plants. This paper discussed the meaning and historical development of medicinal plants. A brief account of phytochemicals (alkaloids and flavonoids) were also given. The plants presented in this paper confirmed the pharmacological activities of these plants and includes;

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“…The plant's smooth muscle relaxant [18], antibacterial [19], antiinflammatory [20], antimalarial [21], anticonvulsant, sedative and central nervous depressant [22] properties have been reported. Its use as a medicinal plant may be attributed to the presence of phytochemicals such as tannins [23], flavonoids [24], saponins [25], alkaloids [26], glycosides, steroids [27], volatile oil [28] and anthocyanins [29]. The plant also contains minerals such as calcium, zinc, potassium, iron, magnesium, lead, copper, manganese, as well as ascorbic acid and amino acids [30].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Antidiarrhoeal Activity of Aqueous Root and Stem Bark Extract of Annona Senegalensis.

Ahmed

Arise²,

Sudi³

2020

International Journal of Life Sciences and Biotechnology

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Diarrhoea is a leading cause of deaths amongst children below five years. Annona senegalensis plant is used traditionally to treat diarrhoea. This study aims at evaluating the antidiarrhoeal potency of the aqueous root and stem bark extracts of Annona senegalensis. Antimicrobial, antioxidant and antidiarrhoeal activity of aqueous extracts of the root bark (ARB), stem bark (ASB) and mixture of stem and root barks (AM) of Annona senegalensis were assessed. Stool inhibition, enteropooling, inhibition of gastro-intestinal motility and electrolyte secretion potential of the extracts were assessed in castor oil-induced diarrhoeic rats following administration of 100, 200 and 400 mg/kg body weight ASB, ARB and AM. The aqueous stem bark (ASB) had the greatest total antioxidant capacity, H2O2 scavenging activity and the ferric reducing assay power. The zone of inhibition of AM against Escherichia coli, Bacillus aureus and Shigella dysentriae was greater than 6 mm. All the extracts inhibited stooling by a percentage ranging from 17-24.7 but was significantly lower (p < 0.05) than the standard drug (30.0%). Inhibition of gastrointestinal tract transit was significantly increased by all the extracts but low dose (100 mg/kg b. wt. of ARB and ASB) significantly increased it the most. The weight and volume of intestinal fluid was significantly decreased by 100 mg/kg b. wt. ARB. The mixture (AM) exhibited synergistic antimicrobial effect. The aqueous stem bark exhibited good antioxidant property, antisecretory and proabsorptive property while the root exhibited good antienteropooling activity. Isolation of bioactive compounds in the extracts should be carried out.

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Phytochemical Constituents of Some Medicinal Plants in South West, Nigeria

Cited by 16 publications

References 8 publications

A mini-review on the pharmacognosy and phytochemistry of a tropical medicinal plant: Annona senegalensis Pers. (Annonaceae)

A mini-review on the pharmacognosy and phytochemistry of a tropical medicinal plant: Annona senegalensis Pers. (Annonaceae)

Phytochemical Compositions in Some Nigerian Medicinal Plants and Their Pharmacological Properties: A Review

Evaluation of the Antidiarrhoeal Activity of Aqueous Root and Stem Bark Extract of Annona Senegalensis.

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