Phytochemical profiling of Opopanax persicus Boiss.

Chemical Composition of the Essential Oils of Three Species of Apiaceae Growing Wild in Sicily: Bonannia graeca, Eryngium maritimum and Opopanax chironium

“…(E)-β-Ionone (3.7%) and (E)geranylacetone (3.3%) were the main components of the carbonylic compounds class (11.7%); of interest is the presence of two coumarins, angelicin (4.5%), the second product of the oil, and psoralen (1.9%). The presence of coumarins is in agreement with previous investigations carried out on the acetone extract of O. chironium [7d] and on the dichloromethane extract of O. persicum, a species endemic of Turkey, Iran, Iraq and Transcaucasia [9].…”

Phytochemistry, Traditional Uses and Pharmacological Properties of the Genus Opopanax W. D. J. Koch: A Mini-Review

“…The acetone extract of the roots of O. chironium from the Sardinian collection was fractionated by column chromatography on silica gel to obtain umbelliprenin (11) (0.020%), imperatorin (12) (0.47%), a mixture of xanthotoxin (13) and bergapten ( 14) (3.4%), heraclenin (15) (0.40%) and heraclenol (16) (0.042%), while a prenylated coumarin, suberosin (17), was found in the fruits (Figure 2). It was noticed that the Sicilian O. chironium (roots and seeds) possessed large amounts of coumarin derivatives, including the major constituent peucedanin (9) (0.56%), along with four other coumarins, marmesin (18), dehydromarmesin methyl ether (19), prantschimgin (20) and smirniorin (21). 4 In addition to coumarins, the Sicilian collection of this plant afforded a mixture of saturated long-chain coniferates, including the main component coniferyl stearate.…”

“…The dichloromethane extract of this species has been revealed the presence of many different types of compounds, mainly linear and angular dihydropyranocoumarins, via many types of chromatographic methods, and this was published as a conference abstract, not a full paper. 19…”

“…46 Some of the angular and linear dihydropyranocoumarins, isolated from O. persicus, showed moderate activity against Plasmodium falciparum K1 strain and Trypanosoma brucei rhodesiense (IC 50 = 3.6 to 6.9 µg/mL) selectivity indices (SI) have been found on L-6 cells of 5.7 to 25, respectively. 19…”

“…13 In addition to the above three accepted species, there are also a few other "unresolved" species included in the genus Opopanax, e.g. 19 Most recently, although a new species, O. bulgaricus Velen. has been cited by the European Environmental Agency, too little information is available about this species to consider it as a real species of this genus.…”